Results 111 to 120 of about 1,128,704 (312)

Using experimental manipulation of questionnaire design and a Kenyan panel to test for the reliability of reported perceptions of climate change and adaptation [PDF]

open access: yes, 2020
While the use of surveys to understand perception of climate change and adaptation is common in research on agriculture, the reliability of aspects of the methodology is still largely untested. In particular there is limited evidence on (i) the degree to
MUNRO Alistair   +1 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Interpretations of Herman Melville’s \u3cem\u3eMoby-Dick\u3c/em\u3e in the Field of Visual Arts [PDF]

open access: yes, 2015
Artistic adaptations of literary classics allow readers to visualize and contextualize some of the most important themes, motifs, scenes, and images in a story that may be difficult to grasp through verbal text alone.
Kudlata, Madeline
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Downhill skiing & climate change adaptation in Wisconsin: perspectives from key stakeholders

open access: yesEnvironmental Research Communications
Climate change is currently impacting various facets of our local systems with many stakeholders and industries working to adapt to these changing conditions.
Austin Holland   +2 more
doaj   +1 more source

« Le librettiste, c’est la cinquième roue du carrosse » : Frédéric Boyer et le monde des chevau-légers de l’opéra

open access: yesE-REA
To work as a librettist is seldom the surest route to stardom. Yet writing the text on which an opera is supposed to soar in the air is by no means a minor task. In a libretto, a composer seeks items that will breathe life into their score.
Patrick ISSERT
doaj   +1 more source

Does privatising public service provision reduce accountability? [PDF]

open access: yes
This paper studies how privatising service provision (shifting control rights and contractual obligations to providers) affects accountability. There are two main effects.
Matthew Ellman
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

High-Intensity Interval Circuit Training Versus Moderate-Intensity Continuous Training on Functional Ability and Body Mass Index in Middle-Aged and Older Women: A Randomized Controlled Trial [PDF]

open access: yes, 2019
The literature suggests that high-intensity interval training (HIIT) is more effective than moderate-intensity continuous training (MICT) to improve functional ability. However, there is no evidence on including HIIT in a circuit programme (HIICT).
Ballesta-García, Ismael   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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