Results 81 to 90 of about 310,924 (269)

A Qualitative Model Demonstrating the Adaptation of Amphibians to Semi-Arid and Arid Habitats: Comparing the Green Toad Bufotes sitibundus (Pallas, 1771) and Pelophylax bedriagae (Camerano, 1882)

Animals
In this brief article, the green toad (Bufotes sitibundus) and the Levant water frog (Pelophylax bedriagae) were compared to better understand the adaptations needed by amphibians, specifically the green toad, to survive in arid regions and to inhabit a ...
Gad Degani
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nature or Nurture: Is the Digestive System of the Pontoporia blainvillei Influenced or Determined by Its Diet?

Animals
The Franciscana (also known as the La Plata River Dolphin) is a small dolphin that lives in the coastal waters of Brazil, Uruguay, and Argentina. This species is considered the most endangered marine mammal in the western South Atlantic Ocean.
Carlos Tostado-Marcos, María Julieta Olocco Diz, Rosario Martín-Orti, Juan-Pablo Loureiro, Ignacio Molpeceres-Diego, Enrique Tendillo-Domínguez, Pilar Pérez-Lloret, Inmaculada Santos-Álvarez, Juncal González-Soriano   +8 more
doaj   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A Greater Capacity of Metallothionein Synthesis: Would it be Sufficient as Explanation for the Absence of Pathological Effects in Marine Mammals with Extremely High Cd Concentrations? A Review

Orbital: The Electronic Journal of Chemistry, 2018
Several studies have shown that marine mammals, especially the oceanic ones, present extremely high Cd concentrations. As the phenomenon of Cd transfer from cephalopods to cetaceans seems to be natural, the most plausible reason for the perpetuation of ...
Paulo Renato Dorneles, André Pinheiro de Almeida, Olaf Malm   +2 more
doaj  

Arctic Plants Under Environmental Stress: A Review

Stresses
Arctic plants inhabit extremely cold environments and are exposed to a range of abiotic stress factors. Arctic species exhibit remarkable adaptability to multiple environmental challenges, including a short growing season, low summer temperatures ...
Natalia Vladimirovna Vasilevskaya
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Downhill skiing & climate change adaptation in Wisconsin: perspectives from key stakeholders

Environmental Research Communications
Climate change is currently impacting various facets of our local systems with many stakeholders and industries working to adapt to these changing conditions.
Austin Holland, Natalie Chin, Hannah Higgins   +2 more
doaj   +1 more source