Results 101 to 110 of about 318,990 (310)

Relationship of physical activity and bone density of Chinese children with intellectual disabilities

, 2011
The 18th International Symposium on Adapted Physical Activity (ISAPA 2011), Paris, France, 4-8 July ...
Chow, BC, Sit, HP
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Statistical Machine Learning for Automatic Assessment of Physical Activity Intensity Using Multi-axial Accelerometry and Heart Rate

, 2011
This work explores the automatic recognition of physical activity intensity patterns from multi-axial accelerometry and heart rate signals. Data collection was carried out in free-living conditions and in three controlled gymnasium circuits, for a total ...
Chausa Fernández, Paloma, Enrique J. Gómez, Gómez, Enrique J., Benito, Pedro José, García Sáez, Gema, Pedro José Benito, Hernando Pérez, María Elena, Gema García-Sáez, García-García, Fernando, Fernando García-García, M. Elena Hernando, Gómez Aguilera, Enrique J., Martínez-Sarriegui, Iñaki, Garcia Garcia, Fernando, Paloma Chausa, Chausa, Paloma, Benito Peinado, Pedro José, Iñaki Martínez-Sarriegui, Martínez Sarriegui, Iñaki, Hernando, M. Elena, García-Sáez, Gema   +20 more
core   +1 more source

Weight status and gender-related differences in motor skills and in child care : based physical activity in young children [PDF]

, 2012
: BACKGROUND: Over the last decades, a decline in motor skills and in physical activity and an increase in obesity has been observed in children. However, there is a lack of data in young children. We tested if differences in motor skills and in physical
Kakebeeke, T. H., Kakebeeke, T.H., Puder Jardena J, Jérôme Barral, Barral Jérôme, Kriemler Susi, Kriemler, S., Tanja H Kakebeeke, Kakebeeke Tanja H, Longchamp, A., Bonvin, A., Jardena J Puder, Puder, J.J., Barral, J., Puder, J. J., Marques-Vidal Pedro, Susi Kriemler, Anouk Longchamp, Marques-Vidal, P., Bonvin Antoine, Antoine Bonvin, Longchamp Anouk, Pedro Marques-Vidal   +22 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Adapted Physical Activity and Ataxia

Ataxia affects the neurological system by impairing balance and motor coordination, which results in significant sensorimotor impairment in both children and adults. Physical activity (PA) has been linked to changes in the structure and functionality of the brain as well as effects on brain plasticity, according to numerous experimental and clinical ...
Katerina Asonitou, Dimitra Koutsouki
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Validity of MTI (Actigraph) for physical activity measurement in children with cerebral palsy [PDF]

, 2010
INTRODUCTION: Physical activity (PA) measurement among children with cerebral palsy (CP) has not been adequately established. CP involves a wide range of disabilities, and the assessment of PA in this population is of importance to the design and ...
Capio, C, Abernethy, B, Sit, C
core