Results 81 to 90 of about 318,990 (310)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Sleep and stress in athletes with disabilities around the 2021 Tokyo Paralympic games during the pandemic

Scientific Reports
This research evaluated the relation and fluctuations in stress and sleep quality in athletes with disabilities (AwD) during the period before and after the 2020 Tokyo Paralympics, amidst the COVID-19 pandemic.
Piotr Kazimierz Urbański, Britton W. Brewer, Michał Starczewski, Kwok Ng, Tomasz Tasiemski, Maciej Tomczak   +5 more
doaj   +1 more source

Assessment and Rehabilitation Intervention of Feeding and Swallowing Skills in Children with Down Syndrome Using the Global Intensive Feeding Therapy (GIFT)

Children
Background: Children with Down syndrome (DS) experience more difficulties with oral motor skills, including chewing, drinking, and swallowing. The present study attempts to measure the preliminary effectiveness of Global Intensive Feeding Therapy (GIFT ...
Silvia Franceschetti, Marco Tofani, Serena Mazzafoglia, Francesca Pizza, Eleonora Capuano, Massimiliano Raponi, Gessica Della Bella, Antonella Cerchiari   +7 more
doaj   +1 more source

Leisure time physical activity in special school environments

, 2011
The 18th International Symposium on Adapted Physical Activity (ISAPA 2011), Paris, France, 4-8 July ...
Sit, CHP, McManus, AM, McKenzie, TL, Cerin, E   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The Use of ABILHAND-Kids in Children with Unilateral Congenital Below-Elbow Deficiencies and Acquired Amputation: An Italian Cross-Sectional Study

Children
Congenital or acquired hand differences, including unilateral below-elbow deficiencies, present complex challenges in pediatric rehabilitation. Surgical management and prosthetic provision represent a big challenge to find a good balance for guaranteeing
Gessica Della Bella, Luigino Santecchia, Paola Luttazi, Giordana Mariani, Lorenzo Pochiero, Alessandra Lacopo, Caterina Delia, Marco Tofani   +7 more
doaj   +1 more source

Physical activity of children in Special School environment

, 2010
The European Congress of Adapted Physical Activity (EUCAPA2010), Jyväskylä, Finland, 6-8 May ...
Sit, HP, McManus, AM, McKenzie, TL, Cerin, E   +3 more
core  

A longitudinal examination of the influence of maturation on physical self-perceptions and the relationship with physical activity in early adolescent girls

, 2009
This longitudinal study investigated the influence of maturation on physical self-perceptions and the relationship with physical activity in early adolescent girls (N = 150; mean age = 12.79 0.31).
Niven, Ailsa, Knowles, Ann Marie, Joan M. Henretty, Ann‐Marie Knowles, Knowles, Ann-Marie, Fawkner, Samantha G., Henretty, Joan M., Fawkner, Samantha, Henretty, Joan, Niven, Ailsa G., Samantha G. Fawkner, Ailsa G. Niven   +11 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The role of school functioning, physical activity, BMI, sex and age in building resilience among Ukrainian refugee children in Poland

Scientific Reports
The study aims to examine the relationship between school functioning, physical activity (PA), sex, Body Mass Index (BMI), age, and resilience in Ukrainian children who migrated to Poland due to the war.
Agata Korcz, Elżbieta Cieśla, Piotr Urbański   +2 more
doaj   +1 more source