Results 101 to 110 of about 7,062,162 (309)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

STRATIFICATED FLOW OF TWO-LAYER LUBRICATION IN THE CLEARANCE OF THRUST BEARING WITH THE INCREASED BEARING CAPACITY

Advanced Engineering Research, 2010
A method of calculation of the thrust plain bearing with adapted profile of the bearing capacity, providing the increased bearing capacity of the bearing, working on the stratified two-layer lubrication in the presence of the porous layer on the surface ...
K.S. AKHVERDIEV, E.E. ALEKSANDROVA, E.V. KRUCHININA, M.A. MUKUTADZE   +3 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

STRATIFICATED FLOW OF TWO-LAYER LUBRICATION IN THE CLEARANCE OF THRUST BEARING WITH THE INCREASED BEARING CAPACITY

Вестник Донского государственного технического университета, 2018
A method of calculation of the thrust plain bearing with adapted profile of the bearing capacity, providing the increased bearing capacity of the bearing, working on the stratified two-layer lubrication in the presence of the porous layer on the surface ...
K.S. AKHVERDIEV, E.E. ALEKSANDROVA, E.V. KRUCHININA, M.A. MUKUTADZE   +3 more
doaj  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Modeling the dynamics of electric vehicle energy consumption based on a realistic driving cycle and battery state of charge estimation

Вестник Самарского университета: Естественнонаучная серия
This paper proposes an algorithm for generating a realistic current profile for laboratory testing of a single lithium-ion battery cell, based on a simplified but physically-informed dynamic model of an electric vehicle’s motion.
M. B. Chernov, A. V. Golubkov
doaj   +1 more source

ROMANIA’S LABOUR FORCE IN REGIONAL PROFILE AFTER THE ACCESSION TO THE EUROPEAN UNION [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2018
The paper approaches the issue of the labour force from Romania in regional profile at a decade after the accession to the European Union. The economic, political, technological and financial changes occurred at different aggregation levels have ...
Mihai Alexandru CHIȚEA
doaj  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Identifying Ocean Submesoscale Activity From Vertical Density Profiles Using Machine Learning

Earth and Space Science
Submesoscale eddies are important features in the upper ocean where they mediate air‐sea exchanges, convey heat and tracer fluxes into ocean interior, and enhance biological production.
Leyu Yao, John R. Taylor, Dani C. Jones, Scott D. Bachman   +3 more
doaj   +1 more source

Severity-adapted graded exercise rehabilitation reduces systemic inflammation and improves functional capacity in hospitalized AECOPD: an assessor-blinded randomized controlled trial

Frontiers in Physiology
BackgroundHospitalized acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is characterized by heightened systemic inflammation and rapid decline in functional capacity.
Hui Zeng, Yue Chen, Yue Chen, Hongmin Ran, Dehua Zhao, Yan Wang, Dandan Fu, Nana Yang, Jimei Luo, Jimei Luo, Lina Ma, Qiuhang Hu, Qiuhang Hu, Lulu Huang, Lulu Huang, Changxiu Li, Luwen Luo, Rong Liu   +17 more
doaj   +1 more source