Results 121 to 130 of about 68,309 (304)
S15: Understanding Factors Affecting Participation in Adapted Physical Activity: Lifetime Engagement
Individuals with disabilities face substantial challenges in achieving adequate physical fitness and maintaining regular physical activity. These challenges are associated not only with functional limitations but also with environmental, social, and ...
Požėrienė, Jūratė, +5 more
core +1 more source
Adapted sports awareness program
, 2023 La situación problema se logró identificar debido a que en las constantes charlas cotidianas con los estudiantes durante las ayudantías en la institución me surge la idea de indagar sobre el deporte adaptado y las personas en situación de discapacidad ...
Posada Silva, Wadis Yovany +1 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Вестник Тамбовского университета. Серия: Гуманитарные наукиImportance. The socialization of children with autism spectrum disorders (hereinafter referred to as ASD) involves a variety of pedagogical approaches to solving existing problems, and physical activity of children with ASD is one of the tools of ...
L. N. Voloshina, D. A. Kosalapova
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2021 The aim – To assess the change in the quality of life of person with intellectual disabilities through adapted physical activity. The goal: 1. To assess the quality of life indicators of persons with intellectual disabilities before participating in the ...
Jasilionytė, Mantė,
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The impact of adapted sports activities on motor development in individuals with intellectual disabilities [PDF]
This study explores the effects of adapted sports activities on motor development in individuals with intellectual disabilities involved in a specialized sports club.
Răducu Popescu, Antoanela Oltean
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source