Results 51 to 60 of about 68,309 (304)
Frontiers in PsychologyBackgroundDepression is common in older adults, often with suboptimal pharmacological responses. Mind-body exercises (MBEs) like Tai Chi, Yoga, and Qigong have emerged as potentially beneficial non-pharmacological interventions.
Fangbo Li +6 more
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Diversity as a starting point for “adapted sport” [PDF]
Journal of Human Sport and Exercise - 2019 - Spring Conferences of Sports Science, 2019 Diversity is a very complicated issue to deal with and it is often not easy to understand it and understand its various nuances. Many times in common thought, the word "diversity" refers to something negative because what is not known inspires fear, and moreover it is even more difficult to make "communicate", and unite, the sphere of diversity with ...
Francesco Peluso Cassese +3 more
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Self-perception and perception of leadership behaviours of Special Olympics Portugal coaches
E-balonmano.com: Revista de Ciencias del Deporte, 2022 Coaches have a fundamental role in the holistic development of their athletes, and when we talk about adapted sports, this prerogative gains more relevance, since sports are a transforming vehicle in the athletes' lives.
Pedro Pires +3 more
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Sport, in general, is a tool for development. It is a very effective way to develop motor skills, since training involves constant repetition of movements in a specific sequence. Adaptive sport, like adaptive physical education, is a social model of rehabilitation. However, unlike physical education, it is aimed at achieving results.
openaire +3 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source