Results 91 to 100 of about 1,241,988 (301)

What about me? Factors affecting individual adaptive coping capacity across different populations [PDF]

open access: yes
 When and why will people adapt to climate change? We conducted a number of studies examining the psychological drivers of individual adaptation to climate change across different populations. We used a variety of methodologies including interviews,
Kerrie Unsworth   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Assessing adaptive capacity to climate change of farmers in Gangetic Plains region, India

open access: yesDiscover Agriculture
India has been identified as one of the most susceptible nations to the impacts of climate change. The present study made an attempt to examine the adaptive capacity of farmers living in the Gangetic Plains of India.
Surendra Singh Jatav   +2 more
doaj   +1 more source

Influencing adaptation processes on the Australian rangelands for social and ecological resilience

open access: yesEcology and Society, 2014
Resource users require the capacity to cope and adapt to climate changes affecting resource condition if they, and their industries, are to remain viable.
Nadine A. Marshall, Chris J. Stokes
doaj   +1 more source

What Do Complex Adaptive Systems Look Like and What Are the Implications for Innovation Policy? [PDF]

open access: yes
This paper explores the use of complex adaptive systems theory in development policy analysis using a case study drawn from recent events in Uganda. It documents the changes that took place in the farming system in Soroti district during an outbreak of ...
Clark, Norman, Hall, Andy
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Spatial Dynamics of Mangrove Changes and Their Adaptive Capacity in Kandanghaur District, Indramayu Regency, West Java Province, Indonesia

open access: yesSriwijaya Journal of Environment
This study aims to analyze mangrove ecosystems' dynamics and adaptive capacity in the Kandanghaur District, Indramayu Regency. This research method uses a spatial approach, collecting mangrove distribution data by analyzing Google Earth satellite images ...
Sodikin Sodikin Sodikin   +3 more
doaj  

Factors influencing household adaptive capacity and its association with food security in Somalia

open access: yesDiscover Sustainability
Building adaptive capacities is a crucial pathway to improving food security of households experiencing multiple shocks. Despite several studies documenting the effect of adaptive capacity on food security in the Horn of Africa, relatively little is ...
Conrad Murendo   +9 more
doaj   +1 more source

The Adaptation Policy Paradox: the Implementation Deficit of Policies Framed as Climate Change Adaptation

open access: yesEcology and Society, 2013
The implementation of adaptation policies suffers from barriers and limits; even though adaptation is now set on the political agendas of developed and developing countries, surprisingly few examples of concrete policy realizations are found in ...
Johann Dupuis, Peter Knoepfel
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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