Results 71 to 80 of about 403,540 (261)

Factors influencing household adaptive capacity and its association with food security in Somalia

open access: yesDiscover Sustainability
Building adaptive capacities is a crucial pathway to improving food security of households experiencing multiple shocks. Despite several studies documenting the effect of adaptive capacity on food security in the Horn of Africa, relatively little is ...
Conrad Murendo   +9 more
doaj   +1 more source

Operationalizing the integrated landscape approach in practice

open access: yesEcology and Society, 2015
The terms "landscape" and "landscape approach" have been increasingly applied within the international environmental realm, with many international organizations and nongovernmental organizations using landscapes as an area of focus for addressing ...
Olivia E. Freeman   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Spatial Dynamics of Mangrove Changes and Their Adaptive Capacity in Kandanghaur District, Indramayu Regency, West Java Province, Indonesia

open access: yesSriwijaya Journal of Environment
This study aims to analyze mangrove ecosystems' dynamics and adaptive capacity in the Kandanghaur District, Indramayu Regency. This research method uses a spatial approach, collecting mangrove distribution data by analyzing Google Earth satellite images ...
Sodikin Sodikin Sodikin   +3 more
doaj  

Assessing adaptive capacity to climate change of farmers in Gangetic Plains region, India

open access: yesDiscover Agriculture
India has been identified as one of the most susceptible nations to the impacts of climate change. The present study made an attempt to examine the adaptive capacity of farmers living in the Gangetic Plains of India.
Surendra Singh Jatav   +2 more
doaj   +1 more source

Adaptive capacity of individuals suffered from diphtheria [PDF]

open access: yesСаратовский научно-медицинский журнал, 2013
The purpose is to reveal functional violations of various organs and systems at persons who have suffered from diphtheria and to develop algorithm of medical examination.
Maleev V.V.   +3 more
doaj  

Influence of livelihoods on climate change adaptation for smallholder farmers in the Mekong Delta Vietnam

open access: yesInternational Journal of Agricultural Sustainability, 2018
Farmers in the Vietnamese Mekong Delta face a wide range of climate-related and hydrological factors which threaten rice production. Smallholder farmers must adapt to climate change to sustain rice production as their central and most important ...
Peter R. Brown   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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