Results 121 to 130 of about 403,540 (261)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

SIN-3 coregulator maintains adaptive capacity to different diets in Caenorhabditis elegans through vitamin B12. [PDF]

G3 (Bethesda)
Palladino F, Bedet C.
europepmc   +1 more source

Threat Perception and Adaptive Capacity of Natural World Heritage Site Management. [PDF]

Environ Manage, 2023
Falk MT, Hagsten E.
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Exploring adaptive capacity to arid heat in remote First Nations communities in Central Australia. [PDF]

Sci Rep
Bhatta M, Baliva G, Pascoe S, Talukder MR, Baghbanian V, Russell D, Ford L, Cass A, Wakerman J, Mathew S.   +9 more
europepmc   +1 more source

Adaptive capacity of the poor

IOP Conference Series: Earth and Environmental Science, 2009
Alexandre Magnan, B Garnaud, R Billé
openaire   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The world's largest cities under climate change and their adaptive capacity to rising heat. [PDF]

Sci Rep
Friesen J, Taubenböck H.
europepmc   +1 more source

Contributions of phenotypic integration, plasticity and genetic adaptation to adaptive capacity relating to drought in Banksia marginata (Proteaceae). [PDF]

Front Plant Sci, 2023
Oyanoghafo OO, Miller AD, Toomey M, Ahrens CW, Tissue DT, Rymer PD.   +5 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source