Results 41 to 50 of about 60,047 (288)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Sequential adaptive strategies for sampling rare clustered populations
Statistical Methods & Applications, 2023 AbstractA new class of sampling strategies is proposed that can be applied to population-based surveys targeting a rare trait that is unevenly spread over an area of interest. Our proposal is characterised by the ability to tailor the data collection to specific features and challenges of the survey at hand.
Mecatti, Fulvia +3 more
openaire +3 more sources
Model-based adaptive cluster sampling
, 2016 Adaptive cluster sampling is useful for exploring populations of rare plant and animal species which cluster together because it allows sampling effort to be concentrated in areas where observed values are high.
Rapley, V E, Welsh, Alan
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
IEEE Access, 2019 Adaptive navigation of scalar fields is a compelling capability in which mobile robotic systems make real-time navigation decisions based on sensed measurements of the environment.
Robert T. Mcdonald +2 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
A Mixture Model for Rare and Clustered Populations Under Adaptive Cluster Sampling
Bayesian Analysis, 2016 Rare populations, such as endangered species, drug users and individuals infected by rare diseases, tend to cluster in regions. Adaptive cluster designs are generally applied to obtain information from clustered and sparse populations. The aim of this work is to propose a unit-level mixture model for clustered and sparse populations when the data are ...
Gonçalves, Kelly C. M. +1 more
openaire +3 more sources
Generalized Exponential-Cum-Exponential Estimator in Adaptive Cluster Sampling
, 2015 In this paper, a generalized exponential-cum-exponential estimator is proposed utilizing the two auxiliary variables based on average values of the networks in adaptive cluster sampling.
Hanif, Muhammad +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source