Results 51 to 60 of about 4,194,931 (278)

Spatiotemporal correlation–based adaptive sampling algorithm for clustered wireless sensor networks

open access: yesInternational Journal of Distributed Sensor Networks, 2018
Energy efficiency is one of the most crucial concerns for WSNs, and almost all researches assume that the process for data transmission consumes more energy than that of data collection.
Wenyu Cai, Meiyan Zhang
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Adaptive sampling in ecology: Key challenges and future opportunities

open access: yesMethods in Ecology and Evolution
Traditional ecological monitoring employs fixed designs, which do not vary over the survey duration. Adaptive sampling, whereby the data already collected informs a sampling design which changes over the course of the study, can provide a more optimal ...
Peter A. Henrys   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Effect of Family-Based Psychological and Educational Interventions on Improving Adaptive Behaviors in Students with Intellectual Impairment [PDF]

open access: yesRavānshināsī-i Afrād-i Istis̠nāyī, 2014
The present study aimed to investigate effects of family-based psychological and educational interventions on improving adaptive behaviors of school students with mental impairment. It followed a semi-experimental research design.
Ahmad Yarmohammadian
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Low-Similarity Client Sampling for Decentralized Federated Learning

open access: yesIEEE Access
Federated Learning (FL) often encounters challenges from statistical heterogeneity caused by non-identical client data distributions. A common approach to mitigate this issue is to cluster clients with similar data and train within each cluster, which ...
Yunseok Kang, Jaeyoung Song
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy