Results 91 to 100 of about 1,720,153 (304)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Two hybrid ARQ error control schemes for near Earth satellite communications [PDF]
Two hybrid Automatic Repeat Request (ARQ) error control schemes are proposed for NASA near Earth satellite communications. Both schemes are adaptive in nature, and employ cascaded codes to achieve both high reliability and throughput efficiency for high ...
Lin, S.
core +4 more sources
Identification and dual adaptive control of a turbojet engine [PDF]
The objective of this paper is to utilize the design methods of modern control theory to realize a dual-adaptive feedback control unit for a highly nonlinear single spool airbreathing turbojet engine.
Leininger, G., Merrill, W.
core +1 more source
Incorporating Rate Adaptation Into Green Networking for Future Data Centers
2013 IEEE 12th International Symposium on Network Computing and Applications, 2013 Despite some proposals for energy-efficient topologies, most of the studies for saving energy in data center networks are focused on traffic engineering, i.e., consolidating flows and switching off unnecessary network devices. The major weakness of this approach is network oscillation brought by the frequent change of network topology when traffic ...
Wang, Lin +4 more
openaire +2 more sources
Adaptive Uplink Data Rate Prediction And Networkselection In A Vehicular Mobile Channel
, 2021 Georgi Nikolov, Georgi Nikolov
openalex +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Adaptive Forecasting of Exchange Rates with Panel Data [PDF]
This article investigates the statistical and economic implications of adaptive forecasting of exchange rates with panel data and alternative predictors.
Alexander Dross, Leonardo Morales-Arias
core
An application of artificial neural network classifier for medical diagnosis [PDF]
, 2013 In recent year, various models have been proposed for medical diagnosis, which broadly can be classified into physical-based approaches and statistical-based approaches. Uncertainty and imprecision are the most important problems in medical diagnosis,
Khaleel Ibraheem, Amjed
core