Results 111 to 120 of about 5,636,137 (307)
Iranian Journal of Electrical and Electronic Engineering, 2008 A low complexity dynamic subcarrier and power allocation methodology for downlink communication in an OFDM-based multiuser environment is developed. The problem of maximizing overall capacity with constraints on total power consumption, bit error rate ...
A. Falahati, M.-R. Ardestani
doaj
Adaptive Bitrate Streaming Over Cellular Networks: Rate Adaptation and Data Savings Strategies
, 2021 Adaptive bitrate streaming (ABR) has become thede factotechnique for videostreaming over the Internet. Despite a flurry of techniques, achieving high quality ABRstreaming over cellular networks remains a tremendous challenge. First, the design ofan ABR scheme needs to balance conflicting Quality of Experience (QoE) metrics suchas video quality, quality
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
MCMC Techniques for Parameter Estimation of ODE Based Models in Systems Biology
Frontiers in Applied Mathematics and Statistics, 2019 Ordinary differential equation systems (ODEs) are frequently used for dynamical system modeling in many science fields such as economics, physics, engineering, and systems biology.
Gloria I. Valderrama-Bahamóndez +2 more
doaj +1 more source
Minimum Bit-Error Rate Design for Space-Time Equalisation-Based Multiuser Detection
, 2006 A novel minimum bit-error rate (MBER) space–time equalization (STE)-based multiuser detector (MUD) is proposed for multiple-receive-antenna-assisted space-division multiple-access systems. It is shown that the MBER-STE-aided MUD significantly outperforms
Chen, S., Hanzo, L., Livingstone, A.
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source