Results 121 to 130 of about 10,854,095 (294)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Adaptive Interface for Complex Software:A Case Study on Macromedia Dreamweaver

open access: yes, 2009
[[abstract]]Professional software has become increasingly complex as advances in technology permit substantially more functionality to be provided to the user so that there are a large number of unused features.
Ya-Jen Cheng
core  

Supporting Knitwear Design Using Case-Based Reasoning [PDF]

open access: yes, 2009
Organised by: Cranfield UniversityKnitwear design is a creative activity that is hard to automate using the computer. The production of the associated knitting pattern, however, is repetitive, time-consuming and error-prone, calling for automation. Our
Richards, P., Ekárt, A.
core   +1 more source

Can Dominant Architectural Culture Influence Cognitive Processes? Architectural Intelligence and AI-Assisted Evaluation

open access: yesBuildings
The concept of technological singularity is discussed here in the context of architecture (of buildings, not software). This is the point at which non-human intelligence is conjectured to surpass ordinary human cognitive limits.
Stephen M. Peña, Nikos A. Salingaros
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

ANALYSIS AND SYSTEMATIZATION OF SOFTWARE INTERFACE DEVELOPMENT METHODS

open access: yesШәкәрім университетінің хабаршысы: Техника ғылымдар
The goal of this research is to analyze and systematize the methods used in software interface (SI) development, as well as to identify the optimal approaches and technologies for creating intuitive and user-friendly interfaces.
E. N. Bopanova   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Assessment of the impacts of climate change on cold region pavement design and operation

open access: yesJournal of Infrastructure Preservation and Resilience
Cold region pavements are subjected to climate impacts, as frost heave and thaw settlement can significantly deteriorate the pavement surface conditions and reduce its service life.
Yusheng Jiang   +3 more
doaj   +1 more source

Utilizing deep learning for intelligent monitoring and early warning of slope disasters in public space design

open access: yesFrontiers in Environmental Science
IntroductionThe increasing frequency of slope disasters in urban and recreational public spaces, driven by climate change, presents significant risks to public safety and sustainable urban design.
Wang Ting, Ying Wang
doaj   +1 more source

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