Results 131 to 140 of about 10,854,095 (294)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Adaptive Distributed Architectural Systems

open access: yes, 2012
Artificial Intelligence has a long and rich history in the field of architecture. Building upon this history, we clarify the term “adaptive” and its use within the field.
A. Schlueter, Z. Nagy, D. Rossi
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Integration of case-based reasoning and model-based reasoning for adaptive design problem solving

open access: yes, 1989
In the case-based approach to design, a novel problem is solved by adapting a design known to solve a related problem. Adapting a known design to solve a related problem by the commonly used methods of heuristic association and search, however, can be ...
Goel, Ashok Kumar, A. Goel
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Supporting authoring of adaptive hypermedia [PDF]

open access: yes
It is well-known that students benefit from personalised attention. However, frequently teachers are unable to provide this, most often due to time constraints.
Hendrix, Maurice
core  

A Performance Analysis of Two Approximate Adaptive Designs

open access: yes, 2005
The performance of function approximator based adaptive control designs may scale badly with approximator dimension [1]. For a simple system class, both projection based designs and multi-resolution approximation based designs have been shown to have ...
French, Mark
core   +1 more source

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