Results 121 to 130 of about 1,920,879 (284)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Tests and classification methods in adaptive designs with applications. [PDF]
J Appl Stat, 2023 Chen DQ, Mao SQ, Niu XF.
europepmc +1 more source
Adapting and Designing Spaces: Children and their Schools
Center for Educational Policy Studies Journal, 2011 In schools, children experience their environment on three different levels: firstly, they constantly make spatial decisions by positioning themselves in relation to others and organising their immediate environment; secondly, they can potentially contribute to shaping the classroom spaces; and, thirdly, they are confronted with the designed school as ...
openaire +7 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
A Brief Overview of Adaptive Designs for Phase I Cancer Trials. [PDF]
Cancers (Basel), 2022 Saxena A +7 more
europepmc +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
, 2019 Muffinjaw Designs work featured at USA Marx Library from March 2019 to April 2019. Come enjoy this collection of various sculptures ranging from a variety of mediums like glass and ceramics.https://jagworks.southalabama.edu/vid_presentations/1054 ...
Designs, Muffinjaw
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Combinatorial Designs with Two Singular Values II. Partial Geometric Designs [PDF]
In this and an earlier paper [17] we study combinatorial designs whose incidence matrix has two distinct singular values.These generalize (v, k, ë) designs, and include uniform multiplicative designs and partial geometric designs.Here we study the latter,
Spence, E., Dam, E.R. van
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Sample size determination and evaluation for two-stage adaptive designs of single arm clinical trials based on median event time test. [PDF]
Contemp Clin Trials Commun, 2023 Park Y, Chen Y.
europepmc +1 more source