Results 91 to 100 of about 4,256,847 (295)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Measurement + Control, 2019 This study aims to solve the problem involving the high false alarm rate experienced during the detection process when using the traditional multivariate statistical process monitoring method.
Lei Tan, Peng Li, Aimin Miao, Yong Chen
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A Burst-by-Burst Adaptive Joint-Detection Based CDMA Speech Transceiver
, 2001 A burst-by-burst adaptive speech transceiver is proposed, which can drop its source coding rate and speech quality under transceiver control in order to invoke a more error resilient modem mode amongst less favourable channel conditions.
Liew, TH, Kuan, EL, How, HT, Hanzo, L
core +1 more source
Scientific ReportsThis paper introduces a new probabilistic composite model for the detection of zero-day exploits targeting the capabilities of existing anomaly detection systems in terms of accuracy, computational time, and adaptability.
Ahmed A. Mohamed +3 more
doaj +1 more source
Low-Illumination Parking Scenario Detection Based on Image Adaptive Enhancement
World Electric Vehicle JournalAiming at the problem of easily missed and misdetected parking spaces and obstacles in the automatic parking perception task under low-illumination conditions, this paper proposes a low-illumination parking space and obstacle detection algorithm based on
Xixi Xu +5 more
doaj +1 more source
Adaptive Detection of Design Flaws
Electronic Notes in Theoretical Computer Science, 2005 AbstractCriteria for software quality measurement depend on the application area. In large software systems criteria like maintainability, comprehensibility and extensibility play an important role.My aim is to identify design flaws in software systems automatically and thus to avoid “bad” — incomprehensible, hardly expandable and changeable — program ...
openaire +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Clinical Ophthalmology, 2011 Yoshiyuki Kitaguchi1, Shunji Kusaka1, Tatsuo Yamaguchi2, Toshifumi Mihashi2, Takashi Fujikado11Department of Applied Visual Science, Osaka University Graduate School of Medicine, Osaka, Japan; 2Topcon Research Institute, Itabashi, JapanPurpose: To ...
Tatsuo Yamaguchi +3 more
doaj