Results 151 to 160 of about 809,797 (292)
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Adaptive Estimation and Cooperative Guidance for Active Aircraft Defense in Stochastic Scenario. [PDF]
Sensors (Basel), 2019 Fang F, Cai Y, Yu Z.
europepmc +1 more source
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Optimizing the learning rate for adaptive estimation of neural encoding models. [PDF]
PLoS Comput Biol, 2018 Hsieh HL, Shanechi MM.
europepmc +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Adaptive Estimation of Spatial Clutter Measurement Density Using Clutter Measurement Probability for Enhanced Multi-Target Tracking. [PDF]
Sensors (Basel), 2019 Park SH, Chong SY, Kim HJ, Song TL.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Adaptive Estimation with Partially Overlapping Models. [PDF]
Stat Sin, 2016 Shin S, Fine J, Liu Y.
europepmc +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Validation of a Bayesian Adaptive Estimation Technique in the Stop-Signal Task. [PDF]
PLoS One, 2016 Livesey EJ, Livesey DJ.
europepmc +1 more source