Results 211 to 220 of about 1,011,945 (297)

Evolutionary Diversification and Adaptive Evolution Analysis of the Plant HD-Zip IV Subfamily. [PDF]

Genes (Basel)
Li Y, Liu Z, Qanmber G, Liu L, Shi H, Guo Y, Yu M, Hussain G, Peng F, Zheng K, Li F.   +10 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Data Mining of Sediment Microbiomes of the Tibetan Plateau Revealed a Genomic Repository of Ancient Lineages and Adaptive Evolution of Asgardarchaeota. [PDF]

Research (Wash D C)
Chen X, Wang N, Jiang C, Luo S, Cheng M, Chu D, Hu C, Zhang P, Chen K, Yang F, Xiong J, Ning K, Miao W.   +12 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Metabolic plasticity and adaptive evolution in <i>Fragaria vesca</i>: bridging wild diversity to crop improvement. [PDF]

Front Plant Sci
Pérez-Martín JE, Bonte D, Osorio S, Posé D.   +3 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Regulation of the amh gene promoter activity by SF-1 in sex-reversing Cheilinus undulatus and its adaptive evolution. [PDF]

BMC Genomics
Bu S, Zhu Y, Ji X, Zhang W, Hu C, Wen X, Luo J.   +6 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Comparative Mitogenomics of <i>Channa pyrophthalmus</i> Unveils Orogeny-Driven Speciation and Lineage-Specific Adaptive Evolution in Snakeheads. [PDF]

Animals (Basel)
Luo Q, Liu J, Liu J, Ou M, Fei S, Liu H, Zhang X, Zhao J.   +7 more
europepmc   +1 more source