Results 111 to 120 of about 5,059,929 (339)

Adaptive Filtering Enhances Information Transmission in Visual Cortex

open access: yes, 2006
Sensory neuroscience seeks to understand how the brain encodes natural environments. However, neural coding has largely been studied using simplified stimuli.
A Kohn   +49 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

On Fast Converging Data-Selective Adaptive Filtering

open access: yesAlgorithms, 2018
The amount of information currently generated in the world has been increasing exponentially, raising the question of whether all acquired data is relevant for the learning algorithm process. If a subset of the data does not bring enough innovation, data-
Marcele O. K. Mendonça   +4 more
doaj   +1 more source

A study of the effects of varying the sampling for a simplified version of the Saturn V/S-1C Final report, 15 May 1968 - 31 Aug. 1969 [PDF]

open access: yes
Bending frequency filtering through adaptive sampling for Saturn 5 stage 1C ...
Mc Daniel, W. L., Mitchell, J. R.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Electromyography-Based Respiratory Onset Detection in COPD Patients on Non-Invasive Mechanical Ventilation

open access: yesEntropy, 2019
To optimize long-term nocturnal non-invasive ventilation in patients with chronic obstructive pulmonary disease, surface diaphragm electromyography (EMGdi) might be helpful to detect patient-ventilator asynchrony.
Leonardo Sarlabous   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Application of RLS adaptive filteringin signal de-noising

open access: yesJournal of Measurement Science and Instrumentation, 2014
In view of the problem that noises are prone to be mixed in the signals,an adaptive signal de-noising system based on reursive least squares(RLS)algorithm is introduced.The principle of adaptive filtering and the process flow of RLS algorithm are ...
CHENG Xue-zhen   +3 more
doaj  

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