Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Prediction of movement for adaptive control of an upper limb exoskeleton [PDF]
The 9.5th international symposium on Adaptive Motion of Animals and Machines. Ottawa,Canada (Virtual Platform). 2021-06-22/25.
Helbig, Thomas +5 more
core +2 more sources
Beam pointing error caused by ship motion over the ocean affects the tracking performance of the ship-borne phased array radar. Due to the dynamic nature of the sea environments, the ship-borne phased array radar must be able to compensate for the ship’s
J. Mar, Chen-Chih Liu, M. B. Basnet
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Cleaning ability of rotary NiTi systems with different kinematics
Background The aim of this study was to compare the cleaning ability of rotary NiTi systems with different kinematics: ProTaper Next (PTN) (continuous rotation motion), WaveOne Gold (WOG) (reciprocating motion), and Twisted File Adaptive (TFA) (adaptive ...
Amira Galal Ismail +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
An adaptive balancing robot with exceptional touch sensitivity driven by an analog sensorimotor loop [PDF]
The 9.5th international symposium on Adaptive Motion of Animals and Machines. Ottawa,Canada (Virtual Platform). 2021-06-22/25.
Untergasser, Simon +3 more
core +2 more sources
Two-stage motion artefact reduction algorithm for electrocardiogram using weighted adaptive noise cancelling and recursive Hampel filter. [PDF]
The presence of motion artefacts in ECG signals can cause misleading interpretation of cardiovascular status. Recently, reducing the motion artefact from ECG signal has gained the interest of many researchers.
Fuad A Ghaleb +4 more
doaj +1 more source
Content-Adaptive Motion Rate Adaption For Learned Video Compression
Accepted by PCS ...
Chih Hsuan Lin +2 more
openaire +4 more sources

