Results 111 to 120 of about 2,920,675 (338)
The WHT is unusually well-placed for exploitation of adaptive-optics (AO) technology. The site seeing is excellent (median 0.7 arcsec), dome seeing is negligible, and preliminary studies indicate that most of the atmospheric seeing originates in a well-defined layer at low altitude, which bodes well for future laser-guide-star AO. The Durham group have
openaire +3 more sources
Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller+12 more
wiley +1 more source
In adaptive optics (AO), multiple different incident wavefronts correspond to a same far-field intensity distribution, which leads to a many-to-one mapping.
Xuejing Qiu+4 more
doaj +1 more source
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo+11 more
wiley +1 more source
BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach+11 more
wiley +1 more source
IsoSense: frequency enhanced sensorless adaptive optics through structured illumination
We present IsoSense, a wavefront sensing method that mitigates sample dependency in image based sensorless adaptive optics applications in microscopy. Our method employs structured illumination to create additional, high spatial frequencies in the image ...
Mantas Žurauskas+6 more
semanticscholar +1 more source
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block+8 more
wiley +1 more source
Adaptive optics imaging of the retina
Adaptive optics is a relatively new tool that is available to ophthalmologists for study of cellular level details. In addition to the axial resolution provided by the spectral-domain optical coherence tomography, adaptive optics provides an excellent lateral resolution, enabling visualization of the photoreceptors, blood vessels and details of the ...
Rajani Battu+4 more
openaire +3 more sources
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons+8 more
wiley +1 more source
Although there is an urgent demand, it is still a tremendous challenge to use the coherent optical communication technology to the satellite-to-ground data transmission system especially at large zenith angle due to the influence of atmospheric ...
Mo Chen, Chao Liu, Daoman Rui, H. Xian
semanticscholar +1 more source