Results 91 to 100 of about 136,518 (282)

Infrared Tall Patch-Matrix Model for Single-Frame Low-Contrast Small Target Detection

open access: yesApplied Sciences
Infrared small target detection (IRSTD) task is vital in practical applications. It is still a challenge when the target size is very small and the local signal-to-noise ratio is particularly low.
Yujia Liu, Wei Tang, Xuying Hao, Tao Lei
doaj   +1 more source

Adaptive SMF Coupling Based on Precise-Delayed SPGD Algorithm and Its Application in Free Space Optical Communication

open access: yesIEEE Photonics Journal, 2018
The adaptive coupling of laser beam from space into single-mode fiber (SMF) plays an important role in the fiber-based free space optical communication technology.
Guan Huang   +4 more
doaj   +1 more source

Simulations of Adaptive Optics with a Laser Guide Star for SINFONI

open access: yes, 2004
The SINFONI instrument for ESO's VLT combines integral field spectroscopy and adaptive optics (AO). We discuss detailed simulations of the adaptive optics module.
Brown, Anthony G A   +2 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Quantitative assessment of parameter requirements in a division of focal plane polarimeter

open access: yesScientific Reports
The division of focal plane polarimeter (DoFP) is a widely utilized instrument for target detection and recognition, owing to its excellent real-time performance and compact configuration.
Bowen Lian   +4 more
doaj   +1 more source

Axial range of conjugate adaptive optics in two-photon microscopy

open access: yes, 2015
We describe an adaptive optics technique for two-photon microscopy in which the deformable mirror used for aberration compensation is positioned in a plane conjugate to the plane of the aberration.
Bifano, Thomas   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Control Bandwidth Promotion of Adaptive Fiber-Optics Collimator and Its Application in Coherent Beam Combination

open access: yesIEEE Photonics Journal, 2018
Adaptive fiber-optics collimator (AFOC) plays an important role in the coherent beam combining (CBC) systems. To improve the control bandwidth, the frequency characteristics of AFOC are measured, and an accurate transfer function model is established ...
Guan Huang   +4 more
doaj   +1 more source

The Robo-AO-2 facility for rapid visible/near-infrared AO imaging and the demonstration of hybrid techniques [PDF]

open access: yes, 2018
We are building a next-generation laser adaptive optics system, Robo-AO-2, for the UH 2.2-m telescope that will deliver robotic, diffraction-limited observations at visible and near-infrared wavelengths in unprecedented numbers.
Baranec, Christoph   +25 more
core   +1 more source

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