Results 111 to 120 of about 1,424,437 (265)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Gender equity issues in astronomy: Facts, fiction, and what the adaptive optics community can do to close the gap

, 2014
Gender equality in modern societies is a topic that never fails to raise passion and controversy, in spite of the large body of research material and studies currently available to inform the general public and scientists alike.
Rigaut, Francois, Sarah Maddison, d'Orgeville, Celine, Elena Masciadri, Masciadri, Elena, Céline D'Orgeville, François Rigaut, Maddison, Sarah T   +7 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

HD-BSNet: A Plug-and-Play Dual-Mechanism Synergistic Enhancement Framework for Small Object Detection

Remote Sensing
In remote sensing and low-altitude unmanned aerial vehicle(UAV) detection scenarios, small target detection is extremely challenging due to the low pixel proportion, sparse features, and complex backgrounds of targets.
Jianwei Wen, Xiangyue Zheng, Nian Pan, Dan Jia, Haiying Wu, Tao Chen, Jin Zhou   +6 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Experimental validation of optimization concepts for focal-plane image processing with adaptive optics [PDF]

, 2018
We show experimental results demonstrating the feasibility of an extremely fast sequential phase-diversity (SPD) algorithm for point sources.
Verhaegen, Michel, Andrei, Raluca M, Doelman, Niek, Fraanje, Rufus, Keller, Christoph U, Korkiakoski, Visa   +5 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The path to visible extreme adaptive optics with MagAO-2K and MagAO-X [PDF]

, 2018
The next generation of extremely large telescopes (ELTs) have the potential to image habitable rocky planets, if suitably optimized. This will require the development of fast high order “extreme” adaptive optics systems for the ELTs.
Xompero, Marco, Pinna, Enrico, Riccardi, Armando, Males, Jared, Briguglio, Runa, Close, Laird, Hinz, Philip, Morzinski, Katie, Guyon, Olivier, Esposito, Simone, Ireland, Michael   +10 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

SFFNet: Shallow Feature Fusion Network Based on Detection Framework for Infrared Small Target Detection

Remote Sensing
Infrared small target detection (IRSTD) is the process of recognizing and distinguishing small targets from infrared images that are obstructed by crowded backgrounds.
Zhihui Yu, Nian Pan, Jin Zhou
doaj   +1 more source