Results 31 to 40 of about 16,964 (253)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Multi-Aperture Adaptive Fiber-Coupled Free-Space Optical Communication System: Scintillation Mitigation and Turbulence Compensation Experiment Based on Gamma-Gamma Channel Modeling

IEEE Photonics Journal
Free-space optical communication is an effective alternative solution to address the “last mile” bottleneck in fiber-optic communication systems.
Ziting Pan, Yuting Li, Yijie Shen, Ziqiang Li, Guan Huang, Chao Geng, Xinyang Li   +6 more
doaj   +1 more source

Adaptive optics based on machine learning: a review

Opto-Electronic Advances, 2022
Adaptive optics techniques have been developed over the past half century and routinely used in large ground-based telescopes for more than 30 years. Although this technique has already been used in various applications, the basic setup and methods have ...
Youming Guo, Libo Zhong, Lei Min, Jiaying Wang, Yu Wu, Kele Chen, Kai Wei, Changhui Rao   +7 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Non-Appearance-Based Discrimination of UAVs and Birds in Optical Remote Sensing: Using Kinematic and Time–Frequency Features

Drones
Unmanned aerial vehicles (UAVs) and birds are typical low-altitude small targets in optical remote sensing, often occupying only a few pixels and exhibiting highly similar appearances, which limits the effectiveness of appearance-based discrimination at ...
Yifei Yao, Jiazhou Geng, Guiting Chen, Tao Lei, Lvjiyuan Jiang, Yi Cui   +5 more
doaj   +1 more source

A Real-Time Measurement System for Atmospheric Turbulence Intensity and Distribution Based on the GLAO System

Applied Sciences, 2023
Measuring the intensity and distribution of atmospheric optical turbulence at large-aperture astronomical telescope sites is crucial to optimizing turbulence correction for different layers.
Xian Ran, Lanqiang Zhang, Hua Bao, Xuejun Rao, Jinsheng Yang, Dingkang Tong, Cheng Wang, Changhui Rao   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

RS-FeatFuseNet: An Integrated Remote Sensing Object Detection Model with Enhanced Feature Extraction

Remote Sensing
With the advancement of satellite and sensor technologies, remote sensing images are playing crucial roles in both civilian and military domains. This paper addresses challenges such as complex backgrounds and scale variations in remote sensing images by
Yijuan Qiu, Jiefeng Xue, Gang Zhang, Xuying Hao, Tao Lei, Ping Jiang   +5 more
doaj   +1 more source

Accurate Light Field Depth Estimation Using Multi-Orientation Partial Angular Coherence

IEEE Access, 2019
Occlusion is a critical issue that affects the accuracy for light field depth estimation. In the presence of occlusions, the photo-consistency property is broken, making ambiguity near occlusion areas.
Zhenghua Guo, Junlong Wu, Xianfeng Chen, Shuai Ma, Licheng Zhu, Ping Yang, Bing Xu   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source