Results 121 to 130 of about 21,086 (310)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Research on adaptive optics image restoration algorithm based on improved joint maximum a posteriori method

Photonic Sensors, 2017
In this paper, we propose a point spread function (PSF) reconstruction method and joint maximum a posteriori (JMAP) estimation method for the adaptive optics image restoration.
Lijuan Zhang, Yang Li, Junnan Wang, Ying Liu   +3 more
doaj   +1 more source

The path to visible extreme adaptive optics with MagAO-2K and MagAO-X [PDF]

, 2018
The next generation of extremely large telescopes (ELTs) have the potential to image habitable rocky planets, if suitably optimized. This will require the development of fast high order “extreme” adaptive optics systems for the ELTs.
Xompero, Marco, Pinna, Enrico, Riccardi, Armando, Males, Jared, Briguglio, Runa, Close, Laird, Hinz, Philip, Morzinski, Katie, Guyon, Olivier, Esposito, Simone, Ireland, Michael   +10 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Intensity adaptive optics

Light: Science & Applications
Adaptive optics (AO) is a powerful tool employed across various research fields, from aerospace to microscopy. Traditionally, AO has focused on correcting optical phase aberrations, with recent advances extending to polarisation compensation.
Zimo Zhao, Yifei Ma, Zipei Song, Jacopo Antonello, Jiahe Cui, Binguo Chen, Jingyu Wang, Bangshan Sun, Honghui He, Lin Luo, Julian A. J. Fells, Steve J. Elston, Martin J. Booth, Stephen M. Morris, Chao He   +14 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Wavefront Correction for Extended Sources Imaging Based on a 97-Element MEMS Deformable Mirror

Micromachines
Adaptive optics (AO) systems are capable of correcting wavefront aberrations caused by transmission media or defects in optical systems. The deformable mirror (DM) plays a crucial role as a component of the adaptive optics system.
Huizhen Yang, Lingzhe Tang, Zhaojun Yan, Peng Chen, Wenjie Yang, Xianshuo Li, Yongqi Ge   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Dynamics of color vision recovery in Vogt-Koyanagi-Harada disease: a longitudinal study using cone contrast test and adaptive optics imaging

Journal of Ophthalmic Inflammation and Infection
Background Vogt-Koyanagi-Harada (VKH) disease affects visual function, but the recovery process of color vision remains incompletely understood.
Tomoko Nakamura, Shinya Abe, Hitoshi Yamazaki, Toshihiko Oiwake, Atsushi Hayashi   +4 more
doaj   +1 more source