Results 61 to 70 of about 2,363,558 (309)

Upward Adaptive Radiation Cascades: Predator Diversification Induced by Prey Diversification [PDF]

, 2018
The value of biodiversity is widely appreciated, but we are only beginning to understand the interplay of processes that generate biodiversity and their consequences for coevolutionary interactions.
Ole Seehausen, Seehausen, Ole, Jakob Brodersen, Post, David M., Brodersen, Jakob, David M. Post   +5 more
core   +1 more source

A New Mechanism for Recurrent Adaptive Radiations [PDF]

The American Naturalist, 2007
Models of adaptive radiation through intraspecific competition have attracted mounting attention. Here we show how extending such models in a simple manner, by including a quantitative trait under weak directional selection, naturally leads to rich macroevolutionary patterns involving recurrent adaptive radiations and extinctions.
Ito, H.C., Dieckmann, U.
openaire   +4 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The Special and General Mechanism of Cyanobacterial Harmful Algal Blooms

Microorganisms, 2023
Cyanobacterial harmful algal blooms (CyanoHABs) are longstanding aquatic hazards worldwide, of which the mechanism is not yet fully understood, i.e., the process in which cyanobacteria establish dominance over coexisting algae in the same eutrophic ...
Wenduo Cheng, Somin Hwang, Qisen Guo, Leyuan Qian, Weile Liu, Yang Yu, Li Liu, Yi Tao, Huansheng Cao   +8 more
doaj   +1 more source

Adaptive Radiation and the Topology of Large Phylogenies [PDF]

Evolution, 1993
The idea that some organisms possess adaptive features that make them more likely to speciate and/or less likely to go extinct than closely related groups, suggests that large phylogenetic trees should be unbalanced (more species should occur in the group possessing the adaptive features than in the sister group lacking such features).
Craig, Guyer, Joseph B, Slowinski
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Efficient computation of spinning modal radiation through an engine bypass duct

, 2008
The aim of this work is to accurately and efficiently predict sound radiation out of a duct with flow. The sound propagation inside a generic engine bypass duct, refractions by the shear layer of the exhaust flow, and propagation in the near field are ...
Zhang, Xin, Chen, Xiaoxian, Ma, Zhaokai, Huang, Xun   +3 more
core   +1 more source

LIKELIHOOD OF ANCESTOR STATES IN ADAPTIVE RADIATION [PDF]

Evolution, 1997
Theories of ecological diversification make predictions about the timing and ordering of character state changes through history. These theories are testable by "reconstructing" ancestor states using phylogenetic trees and measurements of contemporary species.
Dolph, Schluter, Trevor, Price, Arne Ø, Mooers, Donald, Ludwig   +3 more
openaire   +2 more sources

Adaptive radiation.

, 2017
Adaptive radiation is the rapid diversification, from a single common ancestor, of a group of species whose members exhibit a diverse array of adaptations and occupy different ecological niches. Numerous adaptive radiations are evident in the primates, past and present, with two of the best-studied examples being the lemurs of Madagascar and the ...
openaire   +4 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source