Results 201 to 210 of about 110,015 (262)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

An Approach to Design Adaptive Clinical Trials With Time-to-Event Outcomes Based on a General Bayesian Posterior Distribution. [PDF]

Stat Med
McGree JM, Overstall AM, Jones M, Mahar RK.   +3 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Rule-adaptive lane-changing trajectory planning method for autonomous vehicles driven by dynamic risk information. [PDF]

Sci Rep
Zhao J, Yan X, Zhou Z, Zhang Z.
europepmc   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Why don't we teach medical students to work in chaos? [PDF]

Front Med (Lausanne)
Jerjes W, Chan SCC, Klingbajl M, Majeed A.   +3 more
europepmc   +1 more source

Cognitive embodied learning for anomaly active target tracking. [PDF]

Commun Eng
Wu Q, Li J, Zhou F, Ji J, Wang H, Liang H, Ma KK.   +6 more
europepmc   +1 more source

Design of a hybrid learning model for establishing consistency in smart grid environment. [PDF]

Sci Rep
Mahendran S, Gomathy B.
europepmc   +1 more source

A novel high-dimensional model for identifying regional DNA methylation QTLs. [PDF]

Biostatistics
Zhao K, Yang AY, Oualkacha K, Zeng Y, Klein K, Hudson M, Colmegna I, Bernatsky S, Greenwood CMT.   +8 more
europepmc   +1 more source