Results 211 to 220 of about 12,788,874 (304)

Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing. [PDF]

Nat Commun
van der Toorn W, Bohn P, Liu-Wei W, Olguin-Nava M, Gribling-Burrer AS, Smyth RP, von Kleist M.   +6 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Real-time genomic characterization of pediatric acute leukemia using adaptive sampling. [PDF]

Leukemia
Geyer J, Opoku KB, Lin J, Ramkissoon L, Mullighan C, Bhakta N, Alexander TB, Wang JR.   +7 more
europepmc   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

How useful is Nanopore adaptive sampling for sequencing <i>Schistosoma mansoni</i> miracidia? [PDF]

Wellcome Open Res
Lim RM, Arme TM, Arinaitwe M, Barungi A, Crellen T, Jacobs A, Pedersen AB, Webster JP, Lamberton PHL.   +8 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Nanopore adaptive sampling to identify the NLR gene family in melon (Cucumis melo L.). [PDF]

BMC Genomics
Belinchon-Moreno J, Berard A, Canaguier A, Chovelon V, Cruaud C, Engelen S, Feriche-Linares R, Le-Clainche I, Marande W, Rittener-Ruff V, Lagnel J, Hinsinger D, Boissot N, Faivre-Rampant P.   +13 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

DASNeRF: depth consistency optimization, adaptive sampling, and hierarchical structural fusion for sparse view neural radiance fields. [PDF]

PLoS One
Zhang Y, Zhang G, Li K, Zhu Z, Wang P, Wang Z, Fu C, Li X, Fan Z, Zhao Y.   +9 more
europepmc   +1 more source