Results 231 to 240 of about 260,991 (264)

Adaptive-sampling algorithms for answering aggregation queries on Web sites

, 2008
Lekeas, PV, Li, C, Afrati, FN
core   +1 more source

Icarust, a real-time simulator for Oxford Nanopore adaptive sampling. [PDF]

Bioinformatics
Munro R, Wibowo S, Payne A, Loose M.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

An Adaptive Sampling Algorithm with Dynamic Iterative Probability Adjustment Incorporating Positional Information. [PDF]

Entropy (Basel)
Liu Y, Chen L, Chen Y, Ding J.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Identifying outbreaks in sewer networks: An adaptive sampling scheme under network's uncertainty. [PDF]

Proc Natl Acad Sci U S A
Baboun J, Beaudry IS, Castro LM, Gutierrez F, Jara A, Rubio B, Verschae J.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Direct sequencing of insect symbionts via nanopore adaptive sampling. [PDF]

Curr Opin Insect Sci
Badger JH, Giordano R, Zimin A, Wappel R, Eskipehlivan SM, Muller S, Donthu R, Soto-Adames F, Vieira P, Zasada I, Goodwin S.   +10 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Rapid Detection of <i>PML::RARA</i> Fusions in Acute Promyelocytic Leukemia: CRISPR/Cas9 Nanopore Sequencing with Adaptive Sampling. [PDF]

Biomolecules
Middlezong W, Stinnett V, Phan M, Phan B, Morsberger L, Klausner M, Ghabrial J, DeMetrick N, Zhu J, James T, Pallavajjala A, Gocke CD, Baer MR, Zou YS.   +13 more
europepmc   +1 more source