Results 111 to 120 of about 6,146,821 (306)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Are immediate-return strategies adaptive?
Argues that the social strategies that James Woodburn characterised as 'immediate return' are adaptive in specified ecological contexts. Woodburn's 'delayed return' strategies constitute a composite category.
Layton, R.H.
core +2 more sources
Strategic management in the changing leasing market environment
The process of strategic management transformation in the modern leasing market, operating at the intersection of the credit and investment sectors in conditions of increased economic turbulence, has been studied. The issue considered in the study is the
A. V. Serinova, T. Yu. Shemyakina
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Social Resilience and Adaptive Strategies of Female-Headed Households in Indonesia
Female-headed households (FHHs), locally referred to as Perempuan Kepala Keluarga (PEKKA), represent a socially vulnerable group facing multiple and intersecting challenges in simultaneously managing productive and reproductive roles.
Tuti Kartika +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
The mangrove forest is a unique ecosystem that supports the local livelihoods of economically disadvantaged people who reside in nearby areas. The purpose of this study was to assess the state of local livelihoods and the contributing factors in ...
Md. Masud Rana +2 more
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
A megaproject is a complex technological-social-natural system, and its “double-edged sword” effect raises significant attention in research on system sustainability.
Faping Shui +4 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source

