Results 61 to 70 of about 294,503 (315)
Hierarchical Adaptive Structural SVM for Domain Adaptation [PDF]
International Journal of Computer Vision, 2016 A key topic in classification is the accuracy loss produced when the data distribution in the training (source) domain differs from that in the testing (target) domain. This is being recognized as a very relevant problem for many computer vision tasks such as image classification, object detection, and object category recognition.
Xu, Jiaolong +3 more
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Free-edge effects of corrugated laminates
Curved and Layered Structures, 2020 Due to their high numerical efficiency, homogenization models are often employed in the analysis of corrugated laminates. They are usually derived assuming periodic behavior in the corrugated direction and generalized plane strain in the out-of-plane ...
Filipovic Daniel T., Kress Gerald R.
doaj +1 more source
Adaptive Index Structures [PDF]
, 2002 Traditional indexes aim at optimizing the node accesses during query processing, which, however, does not necessarily minimize the total cost due to the possibly large number of random accesses. In this paper, we propose a general framework for adaptive indexes that improve overall query cost. The performance gain is achieved by allowing index nodes to
Yufei Tao, Dimitris Papadias
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Subdivide and Conquer: Adapting Non-Manifold Subdivision Surfaces to Surface-Based Representation and Reconstruction of Complex Geological Structures [PDF]
, 2022 Mohammad Moulaeifard +4 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Towards the realization of composite metastructures: A failure analysis of connections
Materials & DesignMetastructures hold significant potential for applications such as adaptive structures and soft robotics. Architectures of fiber-reinforced polymer metastructures may relate to modular arrangement of straight and curved laminates, with their connections ...
Victor Gaultier, Georgios A. Pappas
doaj +1 more source