Results 81 to 90 of about 1,126,735 (301)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Adaptive Index Structures [PDF]

open access: yes, 2002
Traditional indexes aim at optimizing the node accesses during query processing, which, however, does not necessarily minimize the total cost due to the possibly large number of random accesses. In this paper, we propose a general framework for adaptive indexes that improve overall query cost. The performance gain is achieved by allowing index nodes to
Yufei Tao, Dimitris Papadias
openaire   +1 more source

Backpropagation training in adaptive quantum networks

open access: yes, 2009
We introduce a robust, error-tolerant adaptive training algorithm for generalized learning paradigms in high-dimensional superposed quantum networks, or \emph{adaptive quantum networks}.
A. Ferreira   +17 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Free-edge effects of corrugated laminates

open access: yesCurved and Layered Structures, 2020
Due to their high numerical efficiency, homogenization models are often employed in the analysis of corrugated laminates. They are usually derived assuming periodic behavior in the corrugated direction and generalized plane strain in the out-of-plane ...
Filipovic Daniel T., Kress Gerald R.
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Towards the realization of composite metastructures: A failure analysis of connections

open access: yesMaterials & Design
Metastructures hold significant potential for applications such as adaptive structures and soft robotics. Architectures of fiber-reinforced polymer metastructures may relate to modular arrangement of straight and curved laminates, with their connections ...
Victor Gaultier, Georgios A. Pappas
doaj   +1 more source

Parallel computations and control of adaptive structures [PDF]

open access: yes
The equations of motion for structures with adaptive elements for vibration control are presented for parallel computations to be used as a software package for real-time control of flexible space structures.
Alvin, Kenneth F.   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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