Results 101 to 110 of about 4,949,103 (256)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Structural Design of an Adaptive Wing Trailing Edge for Enhanced Cruise Performance

, 2016
Aircraft wings are usually optimized for a specific design point. However, since they operate in a wide variety of flight regimes, some of these have conflicting impacts on aircraft design process, as a single configuration may be efficient in one ...
Ignazio Dimino, Rosario Pecora, CONCILIO, ANTONIO, Ciminello, M., PECORA, ROSARIO, Antonio Concilio, AMOROSO, FRANCESCO, Dimino, I., Monica Ciminello   +8 more
core   +1 more source

Adaptive output feedback control of aircraft flexible modes [PDF]

, 2012
The application of adaptive output feedback augmentative control to the flexible aircraft problem is presented. Experimental validation of control scheme was carried out using a three disk torsional pendulum.
Joel Bordeneuvue Guibe, Ponnusamy, Sangeeth Saagar, Bordeneuve-Guibé, Joël, Sangeeth Saagar Ponnusamy   +3 more
core   +1 more source

Trade-Off Conceptual Design of a Camber Morphing Flap for the Next Generation Hybrid Electrical Aircraft Across the HERWINGT Project

Applied Sciences
Compliant wing morphing devices deal with controlled and smooth adaptation of the subcomponents’ shape to external conditions. Their structural stiffness distribution, typically resulting from an optimization design process, is tailored to ensure large ...
Maria Chiara Noviello, Bernardino Galasso, Ignazio Dimino, Salvatore Ameduri, Antonio Concilio   +4 more
doaj   +1 more source

On the Hysteresis Mechanism of Magnetorheological Fluids

Frontiers in Materials, 2019
In this paper, hysteresis of magnetorheological (MR) fluids is identified from experimental tests following the mechanism of rate-independence and further studied to explore the hysteresis mechanism.
Xian-Xu Bai, Peng Chen, Peng Chen
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Dynamic analysis of magnetorheological elastomer configured sandwich structures

, 2009
The work presented in this thesis is concerned with the investigation of the dynamic behaviour of magnetorheological elastomers (MREs) and smart sandwich structures.
Choi, Won Jun
core   +1 more source

Demonstration of adaptive structure performance on modular micro air vehicle

, 2022
S.2010-2827Demonstration of the performance of adaptive structures on air vehicles in general has been a rather difficult subject. Different reasons such as cost, risk, actuator capability, time and possibly also others have prevented this performance to
Boller, C., Kuo, C.-M.
core   +1 more source