Results 111 to 120 of about 1,126,735 (301)
SensorsProbability of detection (POD) is an acknowledged mean of evaluation for many investigations aiming at detecting some specific property of a subject of interest.
Bernardino Galasso +4 more
doaj +1 more source
Adaptive control of large space structures using recursive lattice filters [PDF]
The use of recursive lattice filters for identification and adaptive control of large space structures is studied. Lattice filters were used to identify the structural dynamics model of the flexible structures.
Goglia, G. L., Sundararajan, N.
core +1 more source
Adaptive multiscale detection of filamentary structures in a background of uniform random points
, 2003 We are given a set of $n$ points that might be uniformly distributed in the unit square $[0,1]^2$. We wish to test whether the set, although mostly consisting of uniformly scattered points, also contains a small fraction of points sampled from some (a ...
Arias-Castro, Ery +2 more
core +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Structure Adaptive Approach for Dimension Reduction
The Annals of Statistics, 2001 We propose a new method of effective dimension reduction for a multi-index model which is based on iterative improvement of the family of average derivative estimates. The procedure is computationally straightforward and does not require any prior information about the structure of the underlying model.
Hristache, Marian +3 more
openaire +6 more sources
Interactions between the hippocampus, prefrontal cortex, and amygdala support complex learning and memory. [PDF]
, 2019 One of the guiding principles of memory research in the preceding decades is multiple memory systems theory, which links specific task demands to specific anatomical structures and circuits that are thought to act orthogonally with respect to each other.
Fanselow, Michael S +2 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
On the Hysteresis Mechanism of Magnetorheological Fluids
Frontiers in Materials, 2019 In this paper, hysteresis of magnetorheological (MR) fluids is identified from experimental tests following the mechanism of rate-independence and further studied to explore the hysteresis mechanism.
Xian-Xu Bai, Peng Chen, Peng Chen
doaj +1 more source
Adaptive Storage Structures [PDF]
, 2023 This thesis introduces three ways to adapt relational database systems to advancements in modern storage technology. First, we propose Mosaic, a storage engine optimized for analytical workloads. Second, we propose Plush, a hashing-based storage solution for transactional workloads on byte-addressable persistent memory. Finally, we introduce Data Pipes,
openaire
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source