Results 91 to 100 of about 870,231 (290)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Energy-Efficient Sector-Based Routing in 3D Wireless Sensor Networks Using Midpoint-Aware Cluster Head Selection

open access: yesJurnal RESTI (Rekayasa Sistem dan Teknologi Informasi)
Energy efficiency is a key concern in three-dimensional Wireless Sensor Networks (3D WSNs), where irregular node distribution can shorten network lifetime.
Nirwana Haidar Hari   +2 more
doaj   +1 more source

Robust fault diagnosis with parameter uncertainties based on bond graph

open access: yesDianzi Jishu Yingyong, 2018
The hybrid system consists of discrete subsystems and continuous subsystems. The variable conversion in the system is complex and the parameters are uncertain, which leads to the high false alarm rate of fault diagnosis.
Peng Dongmei, Pazilai Mahemuti
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Adaptive multi-threshold image segmentation algorithm

open access: yesTongxin xuebao
Aiming at the issues that most existing multi-threshold segmentation methods struggle to accurately locate the optimal threshold combination and face soaring computational complexity with more thresholds, an adaptive multi-threshold image segmentation ...
LONG Jianwu, LI Jihao, ZENG Shuifei
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Adaptive iterative thresholding algorithms for magnetoencephalography (MEG)

open access: yesJournal of Computational and Applied Mathematics, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
M. FORNASIER, PITOLLI, Francesca
openaire   +3 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy