Results 41 to 50 of about 880,054 (288)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Non spontaneous saccadic movements identification in clinical electrooculography using machine learning [PDF]

open access: yes, 2015
In this paper we evaluate the use of the machine learning algorithms Support Vector Machines, K-Nearest Neighbors, CART decision trees and Naive Bayes to identify non spontaneous saccades in clinical electrooculography tests.
Becerra-García, Roberto Antonio   +8 more
core   +1 more source

Threshold-awareness in adaptive cancer therapy.

open access: yesPLoS Computational Biology
Although adaptive cancer therapy shows promise in integrating evolutionary dynamics into treatment scheduling, the stochastic nature of cancer evolution has seldom been taken into account.
MingYi Wang   +2 more
doaj   +1 more source

Adaptive Spike Threshold Enables Robust and Temporally Precise Neuronal Encoding. [PDF]

open access: yesPLoS Computational Biology, 2016
Neural processing rests on the intracellular transformation of information as synaptic inputs are translated into action potentials. This transformation is governed by the spike threshold, which depends on the history of the membrane potential on many ...
Chao Huang   +3 more
doaj   +1 more source

Adaptive quantization by soft thresholding in HEVC [PDF]

open access: yes2015 Picture Coding Symposium (PCS), 2015
The High Efficiency Video Coding (HEVC) reference encoder includes a Uniform Reconstruction Quantization (URQ) method. This block level quantization technique does not take into account the importance of transform coefficients in terms of signal reconstruction. In this paper, we present a transform coefficient level quantization technique based on soft
Lee Prangnell   +2 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Confidence Level and Sensitivity Limits in High Contrast Imaging

open access: yes, 2007
In long adaptive optics corrected exposures, exoplanet detections are currently limited by speckle noise originating from the telescope and instrument optics, and it is expected that such noise will also limit future high-contrast imaging instruments for
Bruce Macintosh   +8 more
core   +1 more source

A Real-Time Cycle Slip Detection and Repair Method Based on Ionospheric Delay Prediction for Undifferenced Triple-Frequency BDS Signals

open access: yesIEEE Access, 2021
The detection and repair of cycle slips are key steps in high-accuracy GNSS (Global Navigation Satellite System) data processing using carrier phase observations.
Chenxi Zhang   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Adaptive Complex Contagions and Threshold Dynamical Systems [PDF]

open access: yes, 2013
A broad range of nonlinear processes over networks are governed by threshold dynamics. So far, existing mathematical theory characterizing the behavior of such systems has largely been concerned with the case where the thresholds are static.
Chang, Leon   +4 more
core  

Home - About - Disclaimer - Privacy