Bibliometric Study of Adaptogens in Dermatology: Pharmacophylogeny, Phytochemistry, and Pharmacological Mechanisms [PDF]
Drug Design, Development and Therapy, 2023 Xiao-Xing Liu,1– 3 Chun-Yu Chen,1– 3 Li Li,1– 3 Miao-Miao Guo,1– 3 Yi-Fan He,1– 3 Hong Meng,1– 3 Yin-Mao Dong,1– 3 Pei-Gen Xiao,4 Fan Yi1– 3 1Beijing Key Laboratory of Plant Resources Research and Development, College of Chemistry and Materials ...
Fan Yi Pr
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Network Pharmacology of Adaptogens in the Assessment of Their Pleiotropic Therapeutic Activity [PDF]
Pharmaceuticals, 2022 The reductionist concept, based on the ligand–receptor interaction, is not a suitable model for adaptogens, and herbal preparations affect multiple physiological functions, revealing polyvalent pharmacological activities, and are traditionally used in ...
Alexander G Panossian, Thomas Efferth
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Harder, better, faster, stronger? Retrospective chart review of adverse events of interactions between adaptogens and antidepressant drugs [PDF]
Frontiers in Pharmacology, 2023 Aim: We aimed to systematically evaluate the prevalence and clinical characteristics of adverse events associated with the adaptogens and antidepressant drug interactions in a retrospective chart review.Methodology: A total of 1,816 reports of adverse ...
Marcin Siwek
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Plant Adaptogens—History and Future Perspectives [PDF]
Nutrients, 2021 Adaptogens are synthetic compounds (bromantane, levamisole, aphobazole, bemethyl, etc.) or plant extracts that have the ability to enhance the body’s stability against physical loads without increasing oxygen consumption. Extracts from Panax ginseng, Eleutherococcus senticosus, Rhaponticum carthamoides, Rhodiola rosea, and Schisandra chinensis are ...
Velislava Todorova +2 more
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Adaptogens in Long-Lasting Brain Fatigue: An Insight from Systems Biology and Network Pharmacology. [PDF]
Pharmaceuticals (Basel)Long-lasting brain fatigue is a consequence of stroke or traumatic brain injury associated with emotional, psychological, and physical overload, distress in hypertension, atherosclerosis, viral infection, and aging-related chronic low-grade inflammatory ...
Panossian A, Lemerond T, Efferth T.
europepmc +2 more sources
Two Sides of the Same Coin for Health: Adaptogenic Botanicals as Nutraceuticals for Nutrition and Pharmaceuticals in Medicine. [PDF]
Pharmaceuticals (Basel)Background: Adaptogens, commonly used as traditional herbal medicinal products for the relief of symptoms of stress, such as fatigue and exhaustion, belong to a category of physiologically active compounds related to the physiological process of ...
Panossian A, Lemerond T.
europepmc +2 more sources
Pharmaceuticals, 2010 Adaptogens were initially defined as substances that enhance the “state of nonspecific resistance” in stress, a physiological condition that is linked with various disorders of the neuroendocrine-immune system.
Alexander G Panossian
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Adaptogenic Effects of Mushroom Blend Supplementation on Stress, Fatigue, and Sleep: A Randomised, Double-Blind, and Placebo-Controlled Trial. [PDF]
Brain BehavIn a randomized, double‐blind, placebo‐controlled trial, 50 moderately to severely stressed adults received Restake or placebo for 12 weeks. Psychological outcomes, including anxiety, depression, fatigue, perceived stress, and sleep quality, were evaluated alongside stress‐related biomarkers.
Hisamuddin AS +7 more
europepmc +2 more sources
Understanding adaptogenic activity: specificity of the pharmacological action of adaptogens and other phytochemicals [PDF]
Annals of the New York Academy of Sciences, 2017 AbstractAdaptogens are stress‐response modifiers that increase an organism's nonspecific resistance to stress by increasing its ability to adapt and survive. The classical reductionist model is insufficiently complex to explain the mechanistic aspects of the physiological notion of “adaptability” and the adaptogenic activity of adaptogens.
Alexander G Panossian
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Chinese Medicine, 2018 Modern studies have shown that adaptogens can non-specifically enhance the resistance of human body under a wide range of external stress conditions with a multi-targeted and multi-channel network-like manner, especially by affect the immune-neuro ...
Hong Meng, Fan Yi Pr, Pei-Gen Xiao
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