Results 71 to 80 of about 34,023 (303)

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang   +7 more
wiley   +1 more source

Self‐Driving Laboratory Optimizes the Lower Critical Solution Temperature of Thermoresponsive Polymers

open access: yesAdvanced Intelligent Discovery, EarlyView.
A low‐cost, self‐driving laboratory is developed to democratize autonomous materials discovery. Using this "frugal twin" hardware architecture with Bayesian optimization, the platform rapidly converges to target lower critical solution temperature (LCST) values while self‐correcting from off‐target experiments, demonstrating an accessible route to data‐
Guoyue Xu, Renzheng Zhang, Tengfei Luo
wiley   +1 more source

Data‐Driven High‐Throughput Volume Fraction Estimation From X‐Ray Diffraction Patterns

open access: yesAdvanced Intelligent Discovery, EarlyView.
Long exposure times and the need for manual evaluation limit the use of X‐ray diffraction in high‐throughput applications. This study presents a data‐driven approach addressing both issues. HiVE (a method for High‐throughput Volume fraction Estimation) performs composition estimation for high‐noise XRD patterns produced using polychromatic emission ...
Hawo H. Höfer   +6 more
wiley   +1 more source

Adaptation and norming of the Alzheimer's Disease Assessment Scale for Spain (ADAS) (NORMACODEM) (II)

open access: yes, 1997
This report is part of a project for norming cognitive and functional instruments that assess dementia (NORMACODEM). To adapt and norm the Alzheimer's Disease Assessment Scale (ADAS) for use in Spain.
Santacruz, P.   +21 more
core   +1 more source

In Situ Contact Angle Measurement for Autonomous Spin Coating in Self‐Driving Labs

open access: yesAdvanced Intelligent Discovery, EarlyView.
A vision‐based add‐on transforms commercial spin coaters into autonomous modules of Self‐Driving Labs. Combining a width‐scaled U‐Net with classical geometric analysis, the system simultaneously measures contact angles and estimates substrate pose using a single camera.
Sven Fischer, Micha Hiegle, Holger Röhm
wiley   +1 more source

Reducing soil phosphorus fertility brings potential long-term environmental gains: A UK analysis

open access: yesEnvironmental Research Letters, 2017
Soil phosphorus (P) fertility arising from historic P inputs is a major driver of P mobilisation in agricultural runoff and increases the risk of aquatic eutrophication. To determine the environmental benefit of lowering soil P fertility, a meta-analysis
Paul J A Withers   +8 more
doaj   +1 more source

ADAS 869 Comprehensive Examination

open access: yes, 1991
Course syllabus for ADAS 869 Comprehensive Examination Course description: This is the final course in the MHS-ADAS degree program. The comprehensive examination is intended to assess the student\u27s abilities to analyze, synthesize, and evaluate ...
Blevins, Greg   +2 more
core  

Multiscale and Multi‐Timestep Switching of Multiple Machine Learning Force Fields for Artificial Intelligence‐Driven Materials Simulations

open access: yesAdvanced Intelligent Discovery, EarlyView.
Deep Potential model switching accelerates molecular dynamics by using a faster 4 Å model for most timesteps and periodically applying a high‐accuracy 6 Å model. Validation on solid TiO2 and liquid PEG shows preserved RDF correlations and stable NPT behavior, while NVE energy‐drift analyses identify cases requiring additional validation.
Ryuya Kanda   +6 more
wiley   +1 more source

Measuring pesticides in the atmosphere: current status, emerging trends and future perspectives

open access: yesEnvironmental Sciences Europe
There is a long history in environmental sciences to investigate and understand the fate of chemicals in the environment. For pesticides, this has led to systematic assessments of compounds by both academic and regulatory bodies, particularly for soil ...
Martin Brüggemann   +5 more
doaj   +1 more source

DESH-G model and Preliminary Architecture for Multiple ADAS system

open access: yesInternational Journal of Automotive Engineering, 2019
Various Advanced Driver Assistance Systems (ADAS) become prevailing recently. In this paper, we argue the safety analysis of combined ADAS systems.
Masao Ito
doaj   +1 more source

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