Results 81 to 90 of about 27,751 (240)

Constructing immune and prognostic features associated with ADCP in hepatocellular carcinoma and pan-cancer based on scRNA-seq and bulk RNA-seq

Frontiers in Immunology
AimDespite the significant therapeutic outcomes achieved in systemic treatments for liver hepatocellular carcinoma (LIHC), it is an objective reality that only a low proportion of patients exhibit an improved objective response rate (ORR) to current ...
Zhengwei Zhang, Yuying Li, Zhen Quan, Yapeng Li, Liying Zhu, Shibo Sun, Xiaoning Chen   +6 more
doaj   +1 more source

MOGAD patient autoantibodies induce complement, phagocytosis, and cellular cytotoxicity

JCI Insight, 2023
Myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD) is an inflammatory demyelinating CNS condition characterized by the presence of MOG autoantibodies.
Soumya S. Yandamuri, Beata Filipek, Abeer H. Obaid, Nikhil Lele, Joshua M. Thurman, Naila Makhani, Richard J. Nowak, Yong Guo, Claudia F. Lucchinetti, Eoin P. Flanagan, Erin E. Longbrake, Kevin C. O’Connor   +11 more
doaj   +1 more source

The dynamics of wind-driven intraseasonal variability in the equatorial Indian Ocean [PDF]

, 1992
This commentary provides a discussion of the concept of `bounded rationality' as it applies to the theses advanced by Lopes (1991) and Evans (1991). Lopes's (1991) assessment of the irrationalist consequences of Tversky and Kahneman's (1974) work on ...
名倉, 元樹, McPHADEN, Michael, NAGURA, Motoki, McPHADEN, Michael   +3 more
core   +1 more source

Balanced to Unbalanced Motions at a Submesoscale Front and Energy Transfer From Eddy Splitting

Geophysical Research Letters, Volume 53, Issue 9, 16 May 2026.
Abstract Submesoscale dynamics play a crucial role in energy redistribution in the upper ocean but remain challenging to observe due to their small spatial and temporal scales. We use ship‐based observations of an oceanic submesoscale front sampled at high resolution while repeatedly traversed to observe deformation and splitting of an embedded ...
Cristina Martí‐Solana, Simón Ruiz, T. M. Shaun Johnston, Amala Mahadevan, Ananda Pascual   +4 more
wiley   +1 more source

Mixing at the Margins Drives Nitrate Delivery During Downwelling

Geophysical Research Letters, Volume 53, Issue 9, 16 May 2026.
Abstract Wind‐driven coastal upwelling delivers nutrients to the surface waters and enhances primary productivity. In contrast, downwelling transports nutrient‐depleted water away from the surface and is usually presumed to decrease primary production. Here, we show that processes during downwelling can actually pump nutrients into previously nutrient ...
Bofu Zheng, Andrew J. Lucas, Uwe Send, Kristen Davis, Peter J. S. Franks   +4 more
wiley   +1 more source

High-Frequency Surface Wave Radar Current Measurement Corrections via Machine Learning and Towed Acoustic Doppler Current Profiler Integration

Applied Sciences
This paper proposes an algorithm based on the long short-term memory (LSTM) network to improve the quality of high-frequency surface wave radar current measurements.
Zhaomin Xiong, Chunlei Wei, Fan Yang, Langfeng Zhu, Rongyong Huang, Jun Wei   +5 more
doaj   +1 more source

Variation of Zooplankton Mean Volume Backscattering Strength from Moored and Mobile ADCP Instruments for Diel Vertical Migration Observation

Applied Sciences, 2019
Zooplankton can be detected by using acoustic Doppler current profiler (ADCP) instruments through acquiring the mean volume backscattering strength (MVBS) data.
Angga Dwinovantyo, Henry M. Manik, Tri Prartono, Susilohadi Susilohadi, Tohru Mukai   +4 more
doaj   +1 more source

RRS Discovery Cruise D359, 17 Dec 2010-14 Jan 2011. RAPID moorings cruise report [PDF]

, 2011
This cruise report covers scientific operations conducted during RRS Discovery Cruise D359. Cruise D359 departed from São Antonio, Cape Verde on Friday 17th December 2010 arriving Santa Cruz de Tenerife Friday 14th December 2011.The purpose of the cruise
Cunningham, S.A., et al,
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, Volume 20, Issue 5, Page 1220-1236, May 2026.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Targeting a membrane-proximal epitope on mesothelin increases the tumoricidal activity of a bispecific antibody blocking CD47 on mesothelin-positive tumors

mAbs, 2020
Mesothelin (MSLN) is a cell surface glycoprotein overexpressed in several solid malignancies, including gastric, lung, mesothelioma, pancreatic and ovarian cancers.
Eric Hatterer, Xavier Chauchet, Françoise Richard, Leticia Barba, Valéry Moine, Laurence Chatel, Lucile Broyer, Guillemette Pontini, Tereza Bautzova, Flora Juan, Sebastien Calloud, Nicolas Bosson, Maud Charreton, Krzysztof Masternak, Vanessa Buatois, Limin Shang   +15 more
doaj   +1 more source