Results 21 to 30 of about 1,958 (161)

[Association of the ADCY9 gene and gene-environmental interaction with the susceptibility to childhood bronchial asthma]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi, 2022
Jia JJ, Wei B, Li LX, Ren MY, Zhang SN, Liu J, Zhang YX.   +6 more
europepmc   +2 more sources

Pharmacogenetics of inhaled long-acting beta2-agonists in asthma:a systematic review [PDF]

, 2018
Background: Long-acting beta2-agonists (LABA) are recommended in asthma therapy; however, not all asthma patients respond well to LABA. We performed a systematic review on genetic variants associated with LABA response in patients with asthma.
Ambrose, Basu, Bleecker, Bleecker, Bleecker, Bonini, Calhoun, Cariaso, Cazzola, Chung, Cooper, Currie, Drazen, Drysdale, Farzan, Giubergia, Harada, Jabbal, Jabbal, Kalra, Kersten, Kim, Kim, Konno, Lee, Lee, Lemanske, Leusink, Leusink, Li, Lima, Lipworth, Lipworth, Little, Maagdenberg, Mak, Mak, Manning, Moher, Nyenhuis, O'Byrne, Ortega, Ortega, Ortega, Palmer, Peters, Petrovic-Stanojevic, Rabe, Rebordosa, Reihsaus, Salpeter, Sears, Simons, Slankard, Soleimani, Spector, Tan, Taylor, Taylor, Tonk, Turner, Vijverberg, Wechsler, Wechsler, Wijesinghe, Wu, Yancey, Yawn, Zuurhout   +68 more
core   +14 more sources

Transcriptome Based Estrogen Related Genes Biomarkers for Diagnosis and Prognosis in Non-small Cell Lung Cancer

Frontiers in Genetics, 2021
BackgroundLung cancer is the tumor with the highest morbidity and mortality, and has become a global public health problem. The incidence of lung cancer in men has declined in some countries and regions, while the incidence of lung cancer in women has ...
Sinong Jia, Lei Li, Li Xie, Weituo Zhang, Tengteng Zhu, Biyun Qian, Biyun Qian   +6 more
doaj   +1 more source

Comparative Transcriptomics of Gonads Reveals the Molecular Mechanisms Underlying Gonadal Development in Giant Freshwater Prawns (Macrobrachium rosenbergii)

Journal of Marine Science and Engineering, 2022
The giant freshwater prawn, Macrobrachium rosenbergii, is a prawn that has economic significance throughout the world. It exhibits sex-related growth dimorphism, whereby the males grow significantly more rapidly than the females.
Guang Yang, Zhendong Qin, Zhijie Lu, Rishen Liang, Lijuan Zhao, Gan Pan, Li Lin, Kai Zhang   +7 more
doaj   +1 more source

Genetic architecture and selection of Anhui autochthonous pig population revealed by whole genome resequencing

Frontiers in Genetics, 2022
The genetic resources among pigs in Anhui Province are diverse, but their value and potential have yet to be discovered. To illustrate the genetic diversity and population structure of the Anhui pigs population, we resequenced the genome of 150 pigs from
Wei Zhang, Xiaojin Li, Yao Jiang, Mei Zhou, Linqing Liu, Shiguang Su, Chengliang Xu, Xueting Li, Chonglong Wang   +8 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

British Journal of Pharmacology, Volume 180, Issue S2, Page S289-S373, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jurg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +28 more
wiley   +1 more source

Identification and Characterization of Biomarkers and Their Role in Opioid Addiction by Integrated Bioinformatics Analysis

Frontiers in Neuroscience, 2020
Although numerous studies have confirmed that the mechanisms of opiate addiction include genetic and epigenetic aspects, the results of such studies are inconsistent.
Xiuning Zhang, Xiuning Zhang, Xiuning Zhang, Hailei Yu, Hailei Yu, Rui Bai, Rui Bai, Chunling Ma, Chunling Ma   +8 more
doaj   +1 more source

Developmental origins of diabetes mellitus: Environmental epigenomics and emerging patterns 糖尿病的发育起源:环境表观基因组学和新模式

Journal of Diabetes, Volume 15, Issue 7, Page 569-582, July 2023., 2023
Highlights Interactions of environmental factors and epigenome in early life, via environmentally modified epigenetic markers, affect the transcript profiles of pancreatic islets and peripheral insulin target organs, increasing the susceptibility of developing diabetes.
Hong Zhu, Guolian Ding, Xinmei Liu, Hefeng Huang   +3 more
wiley   +1 more source

Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice

Aging Cell, Volume 22, Issue 5, May 2023., 2023
Bifunctional immunotherapeutic HCW9218 functions as a novel SNC‐reducing and senomorphic agent in mice. Subcutaneous administration of HCW9218 activates NK, innate lymphoid group‐1, and CD8+ T cells, and neutralizes TGF‐ß to reduce senescent cells (SNC‐reducing) and SASP (senomorphic) leading to lower chronic inflammation and restored tissue ...
Niraj Shrestha, Pallavi Chaturvedi, Xiaoyun Zhu, Michael J. Dee, Varghese George, Christopher Janney, Jack O. Egan, Bai Liu, Mark Foster, Lynne Marsala, Pamela Wong, Celia C. Cubitt, Jennifer A. Foltz, Jennifer Tran, Timothy Schappe, Karin Hsiao, Gilles M. Leclerc, Lijing You, Christian Echeverri, Catherine Spanoudis, Ana Carvalho, Leah Kanakaraj, Crystal Gilkes, Nicole Encalada, Lin Kong, Meng Wang, Byron Fang, Zheng Wang, Jin‐an Jiao, Gabriela J. Muniz, Emily K. Jeng, Nicole Valdivieso, Liying Li, Richard Deth, Melissa M. Berrien‐Elliott, Todd A. Fehniger, Peter R. Rhode, Hing C. Wong   +37 more
wiley   +1 more source

Human candidate polymorphisms in sympatric ethnic groups differing in malaria susceptibility in Mali. [PDF]

PLoS ONE, 2013
Malaria still remains a major public health problem in Mali, although disease susceptibility varies between ethnic groups, particularly between the Fulani and Dogon. These two sympatric groups share similar socio-cultural factors and malaria transmission
Bakary Maiga, Amagana Dolo, Ousmane Touré, Victor Dara, Amadou Tapily, Susana Campino, Nuno Sepulveda, Paul Risley, Nilupa Silva, Patrick Corran, Kirk A Rockett, Dominic Kwiatkowski, MalariaGEN Consortium, Taane G Clark, Marita Troye-Blomberg, Ogobara K Doumbo   +15 more
doaj   +1 more source