Results 21 to 30 of about 1,135 (126)
CETP inhibition and ADCY9 genotype: evidence of a qualitative pharmacogenetic interaction in cardiovascular disease? [PDF]
bioRxiv, 2018 Background CETP inhibitors raise circulating concentrations of HDL-cholesterol, and potent inhibitors also lower non-HDL-cholesterol and risk of vascular disease.
Michael V. Holmes, George Davey Smith
semanticscholar +4 more sources
Journal of Clinical Pharmacy and Therapeutics, 2010 What is known and objective: Inhaled combination therapy composing of long‐acting β2‐agonist and corticosteroid has been widely applied in the management of asthma, but observed treatment responses vary.
Seung‐Hyun Kim +4 more
semanticscholar +5 more sources
Decision letter: A sex-specific evolutionary interaction between ADCY9 and CETP
, 2021 Eduardo Tarazona-Santos
semanticscholar +3 more sources
A sex-specific evolutionary interaction between ADCY9 and CETP [PDF]
eLife, 2021 Pharmacogenomic studies have revealed associations between rs1967309 in the adenylyl cyclase type 9 (ADCY9) gene and clinical responses to the cholesteryl ester transfer protein (CETP) modulator dalcetrapib, however, the mechanism behind this interaction is still unknown.
Isabel Gamache +15 more
openalex +6 more sources
A sex-specific evolutionary interaction betweenADCY9andCETP [PDF]
bioRxiv, 2021 Pharmacogenomic studies have revealed associations between rs1967309 in the adenylyl cyclase type 9 (ADCY9) gene and clinical responses to the cholesteryl ester transfer protein (CETP) modulator dalcetrapib, however, the mechanism behind this interaction
Isabel Gamache +15 more
openalex +2 more sources
Cloning, Chromosomal Mapping, and Regulatory Properties of the Human Type 9 Adenylyl Cyclase (ADCY9)
Genomics, 1998 The type 9 adenylyl cyclase (AC9) is a widely distributed adenylyl cyclase that was originally cloned from a mouse cDNA library. Here we report the cloning, chromosomal mapping, and regulatory properties of human AC9 (HGMW-approved symbol ADCY9 ...
Beth M. Hacker +7 more
semanticscholar +5 more sources
European Heart Journal, 2019 The clinical benefits of the cholesterol ester transfer protein (CETP) inhibitor dalcetrapib are dependent on the ADCY9 gene, which encodes adenylate cyclase (AC) type 9 (AC9).
Yohann Rautureau +11 more
semanticscholar +4 more sources
Adenylate cyclase 9 expression level is associated with hormone receptor-positive breast cancer and predicts patient prognosis [PDF]
Nagoya journal of medical scienceAdenylate cyclase family members have recently received attention as novel therapeutic targets. However, the significance of adenylate cyclase 9 (ADCY9) in breast cancer has not been elucidated.
Kayoko Sugino +9 more
semanticscholar +3 more sources
PLoS ONE, 2015 MicroRNAs (miRNAs, micro ribonucleic acids) are pivotal post-transcriptional regulators of gene expression. These endogenous small non-coding RNAs play significant roles in tumorigenesis and tumor progression.
Alexander Schwickert +11 more
semanticscholar +5 more sources