Results 111 to 120 of about 4,479,240 (304)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Financial Performance Value-Added Dairy Operations in New York, Vermont and Wisconsin [PDF]

open access: yes
Federal, state and local governments have funded various efforts to support value added agriculture, often implicitly assuming that the enterprises would be profitable and that the transition from commodity producer to producer-processor-marketer ...
Stephenson, Mark W.   +1 more
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

The effect of bow wave breaking on added resistance

open access: yes, 2021
Stimulated by the energy efficiency indices introduced by the International Maritime Organization, the increased attention for the environment as well as economical pressures emphasize the relevance of accurate resistance estimation for ships. This leads
Hengelmolen, Vera (author)
core  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Kansas Value Added Center annual report

open access: yes, 1992
Kansas Agricultural Value-Added Center -- Communication -- Council Meetings -- Training -- Nutrition Labeling -- Pilot Plant and Research Facilities -- Staff -- Coordination/Cooperation -- Legislative Activities -- Other Activities -- FY92 Expenditures --
Kansas Value Added Center, Kansas State University
core  

Added value of information and information systems: A conceptual approach [PDF]

open access: yes, 2006
Purpose – Information, owing to its nature, has numerous capabilities. Through utilizing these capabilities, information systems can add to the value of information.
Fattahi, Rahmatollah, Afshar, Ebrahim
core   +1 more source

A numerical study of added resistance performance and hydrodynamics of KCS hull in oblique regular waves and estimation of resistance in short-crested irregular waves through spectral method

open access: yesInternational Journal of Naval Architecture and Ocean Engineering
Research on multidirectional waves is increasing as studies on added resistance advance. In this study, the added resistance of the multidirectional regular waves of the KCS hull was estimated by numerical analysis.
Soon-Hyun Lee   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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