Results 221 to 230 of about 2,720,797 (300)

Novel Insights on the Synergistic Mechanism of Action Between the Polycationic Peptide Colistin and Cannabidiol Against Gram-Negative Bacteria. [PDF]

Pharmaceutics
Corleto M, Garavaglia M, Martínez MMB, Weschenfeller M, Montes SU, Aran M, Pellizza L, Faccone D, Maffía PC.   +8 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Loss of FAT1 drives cyclophosphamide resistance in breast cancer via the Wnt/β-Catenin pathway. [PDF]

Int J Biol Sci
Zhong L, Cao D, Zheng C, Zhang L, Xu Y, Zhao S, Liu X, Wei G, Niu G, Xu H, Tang X, Wen J, Harris PWR, Zhang J, He A, Xiang D.   +15 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Application of PVA Membrane Doped with TiO₂ and ZrO₂ for Higher Efficiency of Alkaline Electrolysis Process. [PDF]

Nanomaterials (Basel)
Sladjana M, Dimic Misic K, Milovanovic D, Vujosevic DL, Minic A, Nikolic V, Marceta Kaninski M.   +6 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Study on the Influence Law of Dispersant on the Resistance Value of MWCNTs/PANI Epoxy Semiconducting Coatings. [PDF]

Polymers (Basel)
Du B, Li D, Zhu K, Yue C, Xie J, Gao R.
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Antibiotic-Adjuvants Abolish Resistance Conferred by the <i>Staphylococcus aureus</i> Erythromycin Resistance Methyltransferase in an <i>Escherichia coli</i> Model. [PDF]

ACS Infect Dis
Barber TS, Alumasa JN.
europepmc   +1 more source