Results 101 to 110 of about 926,997 (405)

Drug Addiction: Updating Actions to Habits to Compulsions Ten Years On.

Annual Review of Psychology, 2016
A decade ago, we hypothesized that drug addiction can be viewed as a transition from voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by a transition from prefrontal cortical to striatal control over drug seeking ...
B. Everitt, T. Robbins
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Liver stiffness and associated risk factors among people with a history of injecting drugs: a prospective cohort study

Substance Abuse Treatment, Prevention, and Policy
Background Persons with opioid use disorders (OUD) and persons with substance use disorders (SUD) who inject substances have a reduced life expectancy of up to 25 years compared with the general population.
Karl Trygve Druckrey-Fiskaaen, Jørn Henrik Vold, Tesfaye Madebo, Håvard Midgard, Olav Dalgard, Rafael Alexander Leiva, Lars T. Fadnes, for the INTRO-HCV Study Group   +7 more
doaj   +1 more source

Book review: The globalisation of addiction: a study in poverty of the spirit [PDF]

, 2009
This book review is about 'The globalisation of addiction: a study in poverty of the spirit' by Bruce ...
Davies, John B.
core   +1 more source

Genetics of Addictions [PDF]

Psychiatric Clinics of North America, 2010
Addictions include a group of common, heritable psychiatric illnesses that have multiple psychiatric and medical comorbidities. Robust genetic associations have been found for alcohol dependence, nicotine dependence, and cocaine dependence. Common genetic associations have been found between alcohol dependence and aerodigestive cancers and between ...
Sarah M. Hartz, Laura J. Bierut
openaire   +5 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Experiences with healthy eating among individuals with opioid dependence: insights from a dietary assessment

BMC Nutrition
Background People with substance use disorders often have unhealthy diets, including a limited intake of fruits and vegetables. Additionally, individuals with substance use disorders experience a significantly higher burden of physical and mental health ...
Mohammed Khalid Al-Shibli, Lars Thore Fadnes, Hege Berg Henriksen, Elaheh Javadi Arjmand, Lise Margrete Thomassen, Torgeir Gilje Lid, Siv-Elin Leirvåg Carlsen   +6 more
doaj   +1 more source

Spirituality, Religiosity, Depression, Anxiety, and Drug-Use Consequences During Methadone Maintenance Therapy [PDF]

, 2013
Substance addiction is damaging to the health of persons, families, and society. Often the person with addiction has decreased spirituality and religiosity and suffers from anxiety, depression, or both, increasing the risk for continued substance use and
Piacentine, Linda B.
core   +1 more source

Problem gamblers share deficits in impulsive decision-making with alcohol-dependent individuals [PDF]

, 2009
Aims: Problem gambling has been proposed to represent a ‘behavioural addiction’ that may provide key insights into vulnerability mechanisms underlying addiction in brains that are not affected by the damaging effects of drugs.
American Psychiatric Association, Bechara, Beck, Berlin, Blaszczynski, Bush, Campbell-Meiklejohn, Cardinal, Cavedini, Clark, Clark, Clark, Clark, Crews, Cunningham-Williams, Cunningham-Williams, Dalley, Dom, Drummond, Evenden, Fein, Fellows, Foster, Fuentes, Goudriaan, Goudriaan, Goudriaan, Griffiths, Kagan, Kubota, Leiserson, Lejuez, Lesieur, Lezak, Mazas, Noel, Orford, Owen, Passetti, Petry, Petry, Petry, Pfefferbaum, Potenza, Potenza, Potenza, Potenza, Roca, Rodriguez-Jimenez, Rogers, Rosenthal, Shaffer, Shaffer, Skinner, Slutske, Sproston, Steel, Stockwell, Sullivan, Tavares, Toneatto, Ussher, Verdejo-Garcia, Vitaro, Wardle, Welte, Wray   +66 more
core   +2 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source