Results 101 to 110 of about 960,477 (390)

Prevalence of Internet Addiction during the COVID-19 Outbreak and Its Risk Factors among Junior High School Students in Taiwan

International Journal of Environmental Research and Public Health, 2020
The coronavirus disease 2019 (COVID-19) outbreak has significantly disrupted normal activities globally. During this epidemic, people around the world were expected to encounter several mental health challenges.
Min-Pei Lin
semanticscholar   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Sex Addiction: the Chicken-and-Egg Dilemma of Diagnosis [PDF]

, 2013
In May 2013, the American Psychiatric Association will release the next version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V). Interestingly, sex addiction, despite significant attention from mainstream media, will be omitted from ...
Berry, MD
core  

Book review: The globalisation of addiction: a study in poverty of the spirit [PDF]

, 2009
This book review is about 'The globalisation of addiction: a study in poverty of the spirit' by Bruce ...
Davies, John B.
core   +1 more source

Health-related quality of life of long-term patients receiving opioid agonist therapy: a nested prospective cohort study in Norway

Substance Abuse Treatment, Prevention, and Policy, 2020
Background Opioid dependence carries the highest disease burden of all illicit drugs. Opioid agonist therapy (OAT) is an evidence-based medical intervention that reduces morbidity and mortality. There is limited knowledge on the health-related quality of
Christer Frode Aas, Jørn Henrik Vold, Svetlana Skurtveit, Aaron G. Lim, Sabine Ruths, Kamrul Islam, Jan Erik Askildsen, Else-Marie Løberg, Lars Thore Fadnes, Kjell Arne Johansson, for the INTRO-HCV Study Group   +10 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

What makes mental health and substance use services youth friendly? A scoping review of literature

BMC Health Services Research, 2019
Background There are increasing calls to make mental health and substance use services youth friendly, with hopes of improving service uptake, engagement and satisfaction. However, youth-friendliness in this area has not been clearly defined and there is
Lisa D. Hawke, Kamna Mehra, Cara Settipani, Jaqueline Relihan, Karleigh Darnay, Gloria Chaim, Joanna Henderson   +6 more
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source

Prevalence and predictors of video game addiction: a study based on a national representative sample of gamers [PDF]

, 2015
Video gaming has become a popular leisure activity in many parts of the world, and an increasing number of empirical studies examine the small minority that appears to develop problems as a result of excessive gaming.
C Hagquist, Charlotte Thoresen Wittek, CJ Ferguson, CS Andreassen, CS Peters, D Bhugra, D Williams, D Williams, Daniel Hanss, DL King, DL King, DL King, EJ Kim, F Rehbein, GS Brunborg, GS Brunborg, H Choo, H Cole, H Pontes, Helge Molde, HG Wenzel, HR Eriksen, IBM Corp Released, JP Charlton, JS Lemmens, JS Wiggins, K Kroenke, L Elliot, M Algeria, Mark D. Griffiths, MB Donellan, MD Griffiths, MD Griffiths, PT Costa, RA Mentzoni, RL Thorndike, Rune Aune Mentzoni, Ståle Pallesen, Turi Reiten Finserås, Y Takata   +39 more
core   +1 more source

Experiences with healthy eating among individuals with opioid dependence: insights from a dietary assessment

BMC Nutrition
Background People with substance use disorders often have unhealthy diets, including a limited intake of fruits and vegetables. Additionally, individuals with substance use disorders experience a significantly higher burden of physical and mental health ...
Mohammed Khalid Al-Shibli, Lars Thore Fadnes, Hege Berg Henriksen, Elaheh Javadi Arjmand, Lise Margrete Thomassen, Torgeir Gilje Lid, Siv-Elin Leirvåg Carlsen   +6 more
doaj   +1 more source