Results 131 to 140 of about 926,997 (405)

Affect and the computer game player: the effect of gender, personality, and game reinforcement structure on affective responses to computer game-play [PDF]

, 2006
Previous research on computer games has tended to concentrate on their more negative effects (e.g., addiction, increased aggression). This study departs from the traditional clinical and social learning explanations for these behavioral phenomena and ...
Chumbley, J, Griffiths, MD
core   +1 more source

HOURS OF GAMING OR NON-ACADEMIC COMPUTER USE, SUBSTANCE USE, MENTAL HEALTH STATUS AND SCHOOL PERFORMANCE AMONG TEXAS ADOLESCENCE: FINDINGS FROM THE 2017 YRBS IN TEXAS [PDF]

, 2018
Online gaming activities among adolescents and adults has increased exponentially in the last decade, and mental health issues associated with excessive gaming have drawn attention from health care professionals worldwide (Griffith, 2016).
Gao, Shanxiazi
core   +1 more source

An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, cons and tensions [PDF]

, 2014
BACKGROUND: In an effort to control non-medical use and/or medical abuse of prescription drugs, particularly prescription opioids, electronic prescription drug monitoring programs (PDMP) have been introduced in North-American countries, Australia and ...
Islam, M. Mofizul, McRae, Ian S.
core   +2 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Care considerations in medical assistance in dying for persons with mental illness as the sole underlying medical condition: a qualitative study of patient and family perspectives

BMC Psychiatry
Background Persons with mental illness as their sole underlying medical condition are eligible to access medical assistance in dying (MAiD) in a small number of countries, including Belgium, the Netherlands, Luxemburg and Switzerland.
Vicky Stergiopoulos, Hamer Bastidas-Bilbao, Mona Gupta, Daniel Z. Buchman, Donna E. Stewart, Tarek Rajji, Alexander I. F. Simpson, Mary Rose van Kesteren, Vivien Cappe, David Castle, Roslyn Shields, Lisa D. Hawke   +11 more
doaj   +1 more source

Peer involvement and cross-sector efforts in establishing integrated treatment of hepatitis C virus infection for people with substance use disorders: experiences from Norway

Substance Abuse Treatment, Prevention, and Policy, 2019
Background For people with opioid dependence in Norway, chronic hepatitis C virus (HCV) infections contribute to high mortality and high morbidity. Around 50% of patients in medically assisted rehabilitation (MAR) have been shown to have HCV, and the ...
Ole Jørgen Lygren, Ronny Bjørnestad, Else-Marie Løberg, Martine Lepsøy Bonnier, Vibeke Bråthen Buljovcic, Kjell Arne Johansson, Lars T. Fadnes, for the INTRO-HCV Study Group   +7 more
doaj   +1 more source

Addiction to RUNX in lymphoma [PDF]

, 2016
No abstract ...
Borland, Gillian, Kilbey, Anna, Neil, James C.   +2 more
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

HUBUNGAN KECANDUAN GAME ONLINE DENGAN PERUBAHAN EMOSIONAL PADA ANAK USIA REMAJA [PDF]

Introduction: Addiction is a dependent behavior or condition that is very strong physically or psychologically in doing something, and there is an unpleasant feeling when it cannot be fulfilled.
Lesmana, Agung Ari
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