Results 141 to 150 of about 474,753 (298)

An integrated knowledge mobilization approach to substance use health

Health Research Policy and Systems
The Canadian Centre on Substance Use and Addiction (CCSA) has a mandate to provide national leadership in evidence-informed analysis and knowledge mobilization to advance solutions that reduce substance-related harms. Doing this work effectively requires
Sheena Taha, Shea Wood, Chandni Sondagar, Eftyhia Helis, Doris Payer, Miguel Hernandez-Basurto   +5 more
doaj   +1 more source

Effects of Parenting Attitude and Youth's Subjective Class Identification on Game Addiction

, 2013
Jang YeBeet, Hyerim Lee, Minchul Kim, SeoungHo Ryu, Eui Jun Jeong   +4 more
openalex   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications

Nature Reviews Neuroscience, 2011
Rita Z. Goldstein, N. Volkow
semanticscholar   +1 more source

The transition to compulsion in addiction

Nature Reviews Neuroscience, 2020
C. Lüscher, T. Robbins, B. Everitt
semanticscholar   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

The association of psychological distress and economic and health worries with tobacco smoking behavior during the COVID-19 pandemic: a two-year longitudinal cohort study

BMC Public Health
Background The COVID-19 pandemic and other life events may trigger worries and psychological distress. These impacts may lead to unhealthy behaviors, such as tobacco smoking, but the degree of such associations is unclear.
Silvia Eiken Alpers, Karl Trygve Druckrey-Fiskaaen, Tesfaye Madebo, Jørn Henrik Vold, Ståle Pallesen, Jens Christoffer Skogen, Linn-Heidi Lunde, Silje Mæland, Lars Thore Fadnes   +8 more
doaj   +1 more source

The Effect of Sweet-tasting Foods Addiction on Appetite-related Hormones among Obese Adolescents [PDF]

, 2022
Nour Rezaieg
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

An Integrated Care Pathway for depression in adolescents: protocol for a Type 1 Hybrid Effectiveness-implementation, Non-randomized, Cluster Controlled Trial

BMC Psychiatry
Introduction Our group developed an Integrated Care Pathway to facilitate the delivery of evidence-based care for adolescents experiencing depression called CARIBOU-2 (Care for Adolescents who Receive Information ‘Bout OUtcomes, 2nd iteration).
Darren B. Courtney, Melanie Barwick, Bahar Amani, Andrea T. Greenblatt, Madison Aitken, Karolin R. Krause, Brendan F. Andrade, Kathryn Bennett, Kristin Cleverley, Amanda A. Uliaszek, Claire de Oliveira, Lisa D. Hawke, Jo Henderson, Wei Wang, Priya Watson, Amy Gajaria, Amanda S. Newton, Stephanie Ameis, Jacqueline Relihan, Matthew Prebeg, Sheng Chen, Peter Szatmari   +21 more
doaj   +1 more source