Results 131 to 140 of about 842,308 (362)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Addiction, compulsion, and weakness of the will: A dual process perspective [PDF]

open access: yes, 2016
How should addictive behavior be explained? In terms of neurobiological illness and compulsion, or as a choice made freely, even rationally, in the face of harmful social or psychological circumstances?
Henden, Edmund
core  

Utilizing Social Media for Identifying Drug Addiction and Recovery Intervention

open access: green, 2020
Shalmoli Ghosh   +3 more
openalex   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A qualitative study of experiences with physical activity among people receiving opioid agonist therapy

open access: yesSubstance Abuse Treatment, Prevention, and Policy
Background Physical or mental health comorbidities are common among people with substance use disorders undergoing opioid agonist therapy. As both a preventive and treatment strategy, exercise offers various health benefits for several conditions ...
Einar Furulund   +5 more
doaj   +1 more source

Addiction and Smoking Behaviour in Italy [PDF]

open access: yes
Since the end of the eighties the Becker and Murphy model of rational addiction has been the dominant approach to estimate addiction e ects. The main implication of the model is that public policy, in principle, should not interfere with a fully rational
Silvia Tiezzi
core  

Addiction: Choice or Compulsion? [PDF]

open access: gold, 2013
Edmund Henden   +2 more
openalex   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Healthy eating among people on opioid agonist therapy: a qualitative study of patients’ experiences and perspectives

open access: yesBMC Nutrition
People with substance use disorders often have unhealthy diets, high in sweets and processed foods but low in nutritious items like fruits and vegetables, increasing noncommunicable disease risks.
Einar Furulund   +5 more
doaj   +1 more source

Recreational Use of Nitrous Oxide – a Growing Concern in Europe

open access: yesEmerging Trends in Drugs, Addictions, and Health
Introduction: Nitrous oxide, commonly known as laughing gas, is used medically as an analgesic and anaesthetic. It has been used recreationally for its brief euphoric effects for over 200 years, however, in the last decade, there has been a large ...
J. De Morais   +16 more
doaj   +1 more source

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