Results 251 to 260 of about 474,753 (298)

How addiction fuels innovation: a mixed-methods study on the psychological trade-offs of digital labor in gig economy. [PDF]

Front Psychol
Liu B, Liu V, He K, Ou J.
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Determinants of smartphone addiction among university students in Jordan. [PDF]

BMC Psychol
Al-Rajabi N, Masadeh R, ALBashtawy M, Mahmoud KF, Allari RS, Othman EH, Jarrah SS.   +6 more
europepmc   +1 more source

Men, Women and Substance Abuse – Stories about the road to, the time under, and the way out of addictions.

, 2007
Axelsson, Malin, Eliasson, Nettan
openalex   +1 more source

Dynamic Baseline Variables Predict Treatment Outcomes for Addiction Generally, and Smoking in Particular

, 2014
Jayson Spas
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Public Views About Opioid Overdose and People With Opioid Use Disorder.

JAMA Netw Open
McGinty EE, Gutkind S, Niederdeppe J, Franklin Fowler E, Barry CL.   +4 more
europepmc   +1 more source

Prevalence and Distinct Correlates of Smartphone Addiction, Depressive Symptoms, and Their Comorbidity in College Students. [PDF]

Psychiatry Investig
Shi Y, Zhang X.
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source