Results 261 to 270 of about 361,512 (315)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The relationship between shyness and short video addiction among college students: chain mediating role of social support and basic psychological needs. [PDF]

Front Psychol
Bu X, Li X, Li B, Zhang X.
europepmc   +1 more source

A systematic review of internet addiction in hospitalized adolescents: proposing a hospital-adapted moderated dual mediation model of emotional dysregulation and social compensation. [PDF]

Front Psychiatry
Qi X, He J, Wang Q, Liu S, Zhang L, Zhao J, Ma D, Zhao D.   +7 more
europepmc   +1 more source

Food addiction research in India: a scoping review. [PDF]

Front Public Health
Jain A, Pandey MK, Kashyap RS, Kishor M.
europepmc   +1 more source

The Level of Smartphone Addiction and Its Relationship to High Blood Pressure Among Middle-Aged and Elderly People in Rural Areas of China. [PDF]

Nat Sci Sleep
Cheng L, Zheng Y, Chen X, Wu J, Pan Y, Xiong X, Ye Z.   +6 more
europepmc   +1 more source

The relationship between mindfulness, self-control, and short video addiction among medical students. [PDF]

Front Psychol
Luo Y, Li Y, Wu Q, Shi P.
europepmc   +1 more source

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Addiction

Current Opinion in Neurobiology, 2013
Drug and alcohol addiction is a debilitating disorder characterized by persistent drug-seeking behaviors despite negative physiological, medical, or social consequences. Neurobiological models of addiction propose that the reinforcing effects of addictive drugs are associated with altered neurotransmission within the reward 'mesocorticolimbic ...
Barry J, Everitt, Ulrike, Heberlein
openaire   +4 more sources